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Review
. 2018 Dec 9:2018:1539678.
doi: 10.1155/2018/1539678. eCollection 2018.

Graphene Family Nanomaterials: Properties and Potential Applications in Dentistry

Affiliations
Review

Graphene Family Nanomaterials: Properties and Potential Applications in Dentistry

Ziyu Ge et al. Int J Biomater. .

Abstract

Graphene family nanomaterials, with superior mechanical, chemical, and biological properties, have grabbed appreciable attention on the path of researches seeking new materials for future biomedical applications. Although potential applications of graphene had been highly reviewed in other fields of medicine, especially for their antibacterial properties and tissue regenerative capacities, in vivo and in vitro studies related to dentistry are very limited. Therefore, based on current knowledge and latest progress, this article aimed to present the recent achievements and provide a comprehensive literature review on potential applications of graphene that could be translated into clinical reality in dentistry.

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Figures

Figure 1
Figure 1
Different allotropes of carbon nanostructure: (a) 0D Fullerenes; (b) 1D Carbon Nanotubes; (c) 2D Graphene; (d) 3D Graphite. (e) Graphene Oxide can be synthesized through oxidation of graphite, with common method called Hummers method.
Figure 2
Figure 2
Graphene under scanning electron microscope (SEM) at (a) 100000× magnification, (b) 50000× magnification, (c) 35000× magnification, and (d) 12000× magnification.
Figure 3
Figure 3
Currently, no studies correlating dentistry and GFNs have been done on human subjects. Based on the properties presented in in vivo and in vitro studies, the potential applications of GFNs that could be translate to clinical reality in dentistry were summarized by different dental disciplines.

References

    1. Feng L., Wu L., Qu X. New horizons for diagnostics and therapeutic applications of graphene and graphene oxide. Adv. Mater. 2013;25:168–186. - PubMed
    1. Biju V. Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy. Chemical Society Reviews. 2014;43(3):744–764. doi: 10.1039/c3cs60273g. - DOI - PubMed
    1. Geraldine L. C., et al. A graphene-based physiometer array for the analysis of single biological cells. Sci. Rep. 2014;4:p. 6865. - PMC - PubMed
    1. Zhang Y., Nayak T. R., Hong H., Cai W. Graphene: a versatile nanoplatform for biomedical applications. Nanoscale. 2012;4(13):3833–3842. doi: 10.1039/c2nr31040f. - DOI - PMC - PubMed
    1. Chatterjee N., Eom H.-J., Choi J. A systems toxicology approach to the surface functionality control of graphene-cell interactions. Biomaterials. 2014;35(4):1109–1127. doi: 10.1016/j.biomaterials.2013.09.108. - DOI - PubMed

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