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Case Reports
. 2018 Aug 6:30:250.
doi: 10.11604/pamj.2018.30.250.12263. eCollection 2018.

A three-year-old boy with hypodipsic hypernatremia syndrome

Bousayna Iraqi  1 , Rachid Abilkassem  1 , Nezha Dini  1 , Aomar Agadr  1
Affiliations
Case Reports

A three-year-old boy with hypodipsic hypernatremia syndrome

Bousayna Iraqi et al. Pan Afr Med J. .

Abstract

We describe a three-year-old boy who had a growth and psychomotor retardation associated with inappropriate lack of thirst and vasopressin secretion in the presence of chronic plasma hyperosmolarity. Computed brain tomography revealed bilateral supratentorial sub-ependymal and cortical calcifications. Dissociation in the plasma vasopressin response to osmotic change was demonstrated in this patient. Treatment with a vasopressin analogue, desamino-D-arginine vasopressin (DDAVP) and forced intake of water restored plasma osmolality and serum sodium levels to normal.

Keywords: Brain calcifications; child; hypodipsic hypernatremia syndrome.

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Figures

Figure 1
Figure 1
Cranial CT scan demonstrating bilateral supra-tentorial and sub-ependymal and cortical calcifications
See this image and copyright information in PMC

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