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Case Reports
. 2018 Aug 7:30:259.
doi: 10.11604/pamj.2018.30.259.10787. eCollection 2018.

[Ischemic stroke revealing Fahr's syndrome]

[Article in French]
Nawfal Doghmi  1 , Abdelghafour Elkoundi  1 , Amine Belghiti  1 , Abdelouahed Baite  1 , Charki Haimeur  1
Affiliations
Case Reports

[Ischemic stroke revealing Fahr's syndrome]

[Article in French]
Nawfal Doghmi et al. Pan Afr Med J. .

Abstract
in English, French

Fahr's syndrome is defined as the presence of bilateral intracerebral, symmetrical, nonarteriosclerotic calcifications involving the basal ganglia. Their detection during stroke is exceptional. Phosphocalcium metabolism should be investigated with human parathyroid hormone (HPH) dosage. Diagnosis is based on the evaluation of clinical and laboratory data as well as on radiological imaging. Long-term antiepileptic treatment can cause basal ganglia calcification resulting in Fahr's syndrome. Prognosis is favorable. The correction of phosphocalcium metabolism usually leads to significant improvement.

Le syndrome de Fahr est défini par la présence de calcifications intracérébrales bilatérales et symétriques, non artériosclérotiques, localisées aux noyaux gris centraux. La découverte de celles-ci au cours d’un accident cérébrale ischémique constitue un mode de révélation exceptionnelle de cette affection et doit faire pratiquer une étude du métabolisme phosphocalcique avec dosage de la PTH. L’analyse des signes clinico-biologiques et radiologique est à la base du diagnostic. Un traitement antiépileptique au long cours peut favoriser les calcifications au niveau des noyaux gris centraux et induire le syndrome qui reste de bon pronostic. La correction des troubles du métabolisme phosphocalcique amène souvent une amélioration notable.

Keywords: Fahr’s syndrome; epilepsy; ischemic stroke; phosphocalcium metabolism.

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Figures

Figure 1
Figure 1
Calcifications bilatérale des noyaux gris centraux avec une hypodensité temporale gauche
See this image and copyright information in PMC

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