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Review
. 2018 Aug 30:30:301.
doi: 10.11604/pamj.2018.30.301.14948. eCollection 2018.

Kounis syndrome induced by oral intake of aspirin: case report and literature review

Abdelkader Jalil El Hangouche  1   2   3 , Ouiame Lamliki  1 , Latifa Oukerraj  1 , Taoufiq Dakka  2 , Nawal Doghmi  1 , Jamila Zarzur  1 , Mohammed Cherti  1
Affiliations
Review

Kounis syndrome induced by oral intake of aspirin: case report and literature review

Abdelkader Jalil El Hangouche et al. Pan Afr Med J. .

Erratum in

Abstract

The Kounis-Zavras syndrome is defined as the coincidental occurrence of acute coronary events and hypersensitivity reactions following an allergic reaction including a mast-cell degranulation of vasospastic mediators. This report describes a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma also known as Samter-Beer triad combining nasal polyps, asthma, and aspirin allergy leading to vasospasm and myocardial infarction. All physicians should be aware of The Kounis syndrome and always keep that unique clinical entity in mind to recognize it promptly and direct the therapy at suppressing the allergic reaction.

Keywords: Kounis; aspirin allergy; coronary spasm; myocardial infarction; samter´s triad; zavras syndrome.

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Figures

Figure 1
Figure 1
Coronary angiograms before and after intracoronary nitroglycerin; (A) left coronary angiogram with a tubular severe stenosis in the distal LAD and a subtotal occlusion of the first diagonal; (B) left coronary angiogram after intracoronary nitroglycerin injection; the spasm in the distal LAD is completely relieved, the subtotal occlusion of the diagonal is partially improved; (C) right coronary artery (RCA) with patent stent in the proximal segment and diffuse severe stenosis in the mid to distal vessel; (D) RCA after intracoronary nitroglycerin injection with complete relief of the spasm
Figure 2
Figure 2
Sinus tomography revealing the presence of bilateral nasal polyposis
See this image and copyright information in PMC

References

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