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Case Reports
. 2018 Nov 6;5(6):649-652.
doi: 10.1002/mdc3.12670. eCollection 2018 Nov-Dec.

Myoclonus-Dominant Corticobasal Degeneration

Nuria Caballol  1 , Judith Navarro-Otano  2   3 , Asunción Ávila  1 , Marta Balagué-Marmaña  1 , Raul Martínez-Fernández  4 , Oriol de Fàbregas  5 , Ellen Gelpí  6   7 , Josep Valls-Solé  8 , Eduardo Tolosa  2   3   9
Affiliations
Case Reports

Myoclonus-Dominant Corticobasal Degeneration

Nuria Caballol et al. Mov Disord Clin Pract. .
No abstract available

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Figures

Figure 1
Figure 1
(A) DaT‐SPECT 10 months after first initial symptom demonstrates normal striatal uptake. (B) DaT‐SPECT 3 years after clinical onset shows left putamen uptake. (C–E) Brain MRI 3 years after symptom onset. Axial fluid‐attenuation inversion recovery images demonstrate severe and bilateral left greater than right frontoparietal atrophy.
Figure 2
Figure 2
(A) Hematoxylin‐eosin–stained section reveals frequent enlarged or ballooned neurons that are immunoreactive for hyperphosphorylated Tau (inset; AT8). (B) Immunohistochemistry for hyperphosphorylated Tau reveals a characteristic astrocytic plaque in frontal cortex (AT8 immunohistochemistry). (C) Abundant cellular processes in white matter along with frequent oligodendroglial inclusions in the form of coiled bodies (inset; AT8 immunohistochemistry).
See this image and copyright information in PMC

References

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