Breastfeeding and Type 2 Diabetes: Systematic Review and Meta-Analysis

Abstract

Purpose of review: Breastfeeding has short- and long-term benefits for child health. In this systematic review, we updated a review on the association between breastfeeding and type 2 diabetes.

Recent findings: A meta-analysis published in 2015 reported that breastfeeding protects against type 2 diabetes (pooled odds ratio, 0.65 (95% confidence interval, 0.48; 0.86)). In the present update, we identified three recently published studies. An internet-based study reported that at a mean age of 25.6 years, exclusive breastfeeding in the first 6 months protected against type 2 diabetes (odds ratio, 0.63 (95% confidence interval, 0.41; 0.95)). In a retrospective cohort, those subjects who had been breastfed before hospital discharge were less likely of presenting diabetes (odds ratio, 0.83 (95% confidence interval, 0.69; 0.99)). In a case-control study, the odds of type 2 diabetes in adolescents was lower for those exclusively breastfed at hospital discharge (odds ratio, 0.52 (95% confidence interval, 0.36; 0.74)). In the meta-analysis, the pooled odds ratio was 0.67 (95% confidence interval, 0.56; 0.80). The updated systematic review and meta-analysis suggests that breastfeeding protects from type 2 diabetes.

Keywords: Breastfeeding; Glycemia; Human milk; Type 2 diabetes.