Very long-term results of post-traumatic bone defect reconstruction by the induced membrane technique

Abstract

Introduction: The induced membrane technique for bone defect reconstruction is now well recognized, and short-term results for bone healing are consistent between published reports.

Objectives: To assess very long-term functional results in post-traumatic reconstruction using the induced membrane technique.

Method: Results for 18 patients undergoing bone defect reconstruction by induced membrane were retrospectively analyzed at 10 to 22years' follow-up. Initial lesions were multitissue with infection in 14 cases. Reconstruction concerned the tibia in 14 cases, and the humerus, elbow, radius or ulna in 1 case each. Soft-tissue reconstruction was performed in 17 cases, by free flap (n=8) or pedicle flap (n=9). Fixation used a single-plane external fixator in 15 cases, screwed plate in 1 case (humerus), or intramedullary nail in 1 case (ulna). There was 1 crossover from external fixator to internal plate fixation (radius). Assessment comprised radiology, functional assessment, clinical examination and patient satisfaction. All patients were followed up in individual consultation.

Results: Eight of the 14 patients with lower limb lesions had unrestricted walking distance; 4 resumed leisure sports. Limb shortening ranged from 0.5 to 4cm and was well-tolerated, although dorsiflexion was abolished or limited in most cases. Several patients underwent second procedures to improve limb function: ankle fusion, Achilles lengthening, tendon transfer, or realignment osteotomy. Radiology found a neotubular aspect, indicating peripheral densification and central resorption. Despite the multiple procedures, no patients regretted the original limb-conserving surgery. All reported that it took 2 to 3years after consolidation and resumption of walking to achieve stable final functional improvement. No recurrent sepsis in the reconstruction zone was found.

Conclusion: The present results encourage implementing limb-conserving strategies in young patients after severe multitissue limb trauma, on condition that lesions are properly assessed, notably in terms of infection, and that the reconstruction protocol is feasible and has the patient's consent.

Level of evidence: IV, retrospective series.

Keywords: Bone defect; Bone reconstruction; Induced membrane; Masquelet technique.