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Review
. 2019 Jan 11;20(2):277.
doi: 10.3390/ijms20020277.

Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review

Francesca Zotti  1 , Massimo Albanese  2 , Luigi Fabrizio Rodella  3 , Pier Francesco Nocini  4
Affiliations
Review

Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review

Francesca Zotti et al. Int J Mol Sci. .

Abstract

Background: The aims of this narrative review were to examine up-to-date literature in order to evaluate the effectiveness of arthrocentesis or injections with platelet-rich plasma in temporomandibular affections and to compare them to arthrocentesis alone or with hyaluronic acid (HA) or to hyaluronic acid injections.

Methods: The search of international literature was made on the PMC, PubMed and Cochrane databases, including all full-length text of studies on humans focused on osteoarthritis and disc displacements and their treatment with platelet-rich plasma arthrocentesis or injections. All design studies were included in the review and they were examined for three different outcomes: pain, joint sound and mandibular motion. English papers were only selected.

Results: Even though the low number of studies in this field, arthrocentesis with platelet-rich plasma and platelet-rich plasma injections in temporomandibular disorders' management were found to be effective in reducing pain and joint sound as well as in improving mandibular motion in a maximum follow-up of 24 months.

Conclusion: Comparison to arthrocentesis alone or to HA use in arthrocentesis or by injections provided encouraging results in terms of the effectiveness of platelet-rich plasma use.

Keywords: arthrocentesis; hyaluronic acid; injection; platelet-rich plasma; temporomandibular joint (TMJ); temporomandibular joint disorders (TMD).

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Literature selection process.
See this image and copyright information in PMC

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