Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2019 Feb:128:91-100.
doi: 10.1016/j.lungcan.2018.11.031. Epub 2018 Nov 24.

Clinical characteristics and medical service utilization of lung cancer in China, 2005-2014: Overall design and results from a multicenter retrospective epidemiologic survey

Ju-Fang Shi  1 , Le Wang  2 , Ning Wu  3 , Jun-Ling Li  4 , Zhou-Guang Hui  5 , Shang-Mei Liu  6 , Bo-Yan Yang  7 , Shu-Geng Gao  8 , Jian-Song Ren  2 , Hui-Yao Huang  2 , Juan Zhu  2 , Cheng-Cheng Liu  2 , Jin-Hu Fan  9 , Shi-Jun Zhao  3 , Pu-Yuan Xing  4 , Ye Zhang  5 , Ning Li  7 , Wen-Dong Lei  8 , De-Bin Wang  10 , Yun-Chao Huang  11 , Xian-Zhen Liao  12 , Xiao-Jing Xing  13 , Ling-Bin Du  14 , Li Yang  15 , Yu-Qin Liu  16 , Yong-Zhen Zhang  17 , Kai Zhang  18 , You-Lin Qiao  9 , Jie He  8 , Min Dai  19 ; LuCCRES Group
Affiliations
Multicenter Study

Clinical characteristics and medical service utilization of lung cancer in China, 2005-2014: Overall design and results from a multicenter retrospective epidemiologic survey

Ju-Fang Shi et al. Lung Cancer. 2019 Feb.

Abstract

Objectives: This study aimed to explore the clinical profile and its trajectory of lung cancer on clinicopathological characteristics and medical service utilization in China.

Methods: Patients diagnosed with primary lung cancer in tertiary hospitals during 2005-14 were selected from seven geographic regions of China. Data on clinical characteristics and medical service utilization was extracted from medical record, and the ten-year trends were explored.

Results: A total of 7184 patients were included, the mean age was 58.3 years and the male-to-female-ratio was 2.7. From 2005 to 2014, the proportion of ≥60 year-old patients increased from 41.2% to 56.2% (p < 0.001). The smoking rate decreased from 62.9% to 51.1% (p < 0.001) and the proportion of females increased from 23.5% to 31.9% (p < 0.001). The proportion of advanced stage increased from 41.9% to 47.4% (p < 0.001). Adenocarcinoma's proportion increased from 36.4% to 53.5% (p < 0.001) while that of squamous carcinoma decreased from 45.4% to 34.4% (p < 0.001). The application of chest X-ray dropped from 50.2% to 31.0% (p < 0.001) but that of chest CT increased from 65.8% to 81.4% (p < 0.001). As two main treatment options, chemotherapy (p = 0.290) and surgery (p = 0.497) remained stable. The medical expenditure per patient increased from 40,508 to 66,020 Chinese Yuan (p < 0.001).

Conclusions: The sustaining high smoking exposure, increasing proportion of female patients, advancing clinical stage, shifting of predominant pathology and increasing medical expenditure demonstrate potential challenges and directions on lung cancer prevention and control in China. Despite substantial changes of clinical characteristics, main treatment options remained unchanged, which needs further investigation.

Keywords: China; Clinical epidemiology; Lung cancer; Medical expenditure; Medical service utilization.

PubMed Disclaimer

Publication types

MeSH terms