Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Dec 19:5:e96.
doi: 10.14309/crj.2018.96. eCollection 2018.

Gastric Angiomyolipoma Masquerading as Gastric Malignancy

Divya Achutha Ail  1 , Roopa Rachel Paulose  1 , Abhijit Kalitha  1 , Annie Jojo  1 , Unnikrishnan G  1
Affiliations
Case Reports

Gastric Angiomyolipoma Masquerading as Gastric Malignancy

Divya Achutha Ail et al. ACG Case Rep J. .

Abstract

Gastric angiomyolipoma (AML) is extremely rare, with only 3 cases reported in English literature, all of which presented with upper gastrointestinal bleed, either in the form of hematemesis or melena. A 42-year-old man presented with upper gastrointestinal bleed, the source of which was found to be a large mass in the stomach, which was shown histologically to be gastric AML. This is the fourth but largest tumor (9 × 6 × 5 cm) to be reported to date.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Endoscopic image of the stomach showing a large submucosal lesion with overlying ulceration in the gastric body.
Figure 2
Figure 2
Gross picture showing a large submucosal tumor of stomach, a mass with overlying mucosa (star), and adjacent normal gastric mucosa (white arrow). The inset shows a yellow cut surface with gray and white areas and prominent vessels (arrow).
Figure 3
Figure 3
(A) Hematoxylin and eosin (H&E) stain (50×) showing gastric submucosal lipomatous tumor cells with mucosal ulceration. Inset shows source of bleeding (arrow). (B and C) H&E stain (100×) of triphasic component of tumor comprising adipocytes (arrow with star), thick-walled vessel (black arrow), and smooth muscle emanating from the vessel (arrow with #). (D) Smooth muscle actin stain (100×) highlighting smooth muscles emanating from the vessel wall (arrow).
See this image and copyright information in PMC

References

    1. Minja EJ, Pellerin M, Saviano N, Chamberlain RS. Retroperitoneal extrarenal angiomyolipomas: An evidence-based approach to a rare clinical entity. Case Rep Nephrol. 2012;2012:374107. - PMC - PubMed
    1. Veera RR, Bemalgi SR. Gastric angiomyolipoma, a very rare cause of upper gastrointestinal bleeding: A case report and a brief review of literature. Gastroenterology Res. 2012;5(5):200-4. - PMC - PubMed
    1. John NE, David JG, Robert HY. Tumors of the urinary tract In: Christopher D.M. Fletcher, ed. Diagnostic histopathology of tumors. 4th ed Philadelphia: Elsevier Saunders; 2013:578-80.
    1. Goldblum JR, Folpe AL, Sharon W. Soft tissue tumors showing melanocytic differentiation In: Goldblum JR, Weiss SW, Folpe AL, eds. Enzinger and Weiss's Soft Tissue Tumors. 6th ed Philadelphia: Elsevier Health Sciences; 2014:897-901.
    1. Yang L, Feng XL, Shen S, Shan L, Zhang HF, Liu XY, Lv N. Clinicopathological analysis of 156 patients with angiomyolipoma originating from different organs. Oncol Lett. 2012;3(3):586–90. - PMC - PubMed

Publication types