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Comment
. 2019 Apr;16(4):204-206.
doi: 10.1038/s41575-019-0108-z.

Precision dietary supplementation based on personal gut microbiota

Yu-Jui Yvonne Wan  1 , Prasant Kumar Jena  2
Affiliations
Comment

Precision dietary supplementation based on personal gut microbiota

Yu-Jui Yvonne Wan et al. Nat Rev Gastroenterol Hepatol. 2019 Apr.

Abstract

Over the past decade, many studies have revealed the importance of the gut microbiome in disease development and treatment, including in cancer. Because both host genetics and the gut microbiome can influence host phenotype and treatment outcome, there is an urgent need to develop precision medicine and personalize dietary supplementation based on an individual’s microbiome.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

Figures

Fig. 1 |
Fig. 1 |. The effect of short-chain fatty acids in health and disease.
Short-chain fatty acids, which are produced through the fermentation of dietary fibres by the gut microbiota, have effects on many disease processes. GLP-1, glucagon-like peptide 1.
See this image and copyright information in PMC

Comment on

  • Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.
    Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD Jr, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, Kennett MJ, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M. Singh V, et al. Cell. 2018 Oct 18;175(3):679-694.e22. doi: 10.1016/j.cell.2018.09.004. Cell. 2018. PMID: 30340040 Free PMC article.

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