Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jan 14;9(1):98.
doi: 10.3390/nano9010098.

Plasma and Nanomaterials: Fabrication and Biomedical Applications

Affiliations
Review

Plasma and Nanomaterials: Fabrication and Biomedical Applications

Nagendra Kumar Kaushik et al. Nanomaterials (Basel). .

Abstract

Application of plasma medicine has been actively explored during last several years. Treating every type of cancer remains a difficult task for medical personnel due to the wide variety of cancer cell selectivity. Research in advanced plasma physics has led to the development of different types of non-thermal plasma devices, such as plasma jets, and dielectric barrier discharges. Non-thermal plasma generates many charged particles and reactive species when brought into contact with biological samples. The main constituents include reactive nitrogen species, reactive oxygen species, and plasma ultra-violets. These species can be applied to synthesize biologically important nanomaterials or can be used with nanomaterials for various kinds of biomedical applications to improve human health. This review reports recent updates on plasma-based synthesis of biologically important nanomaterials and synergy of plasma with nanomaterials for various kind of biological applications.

Keywords: biomedical applications; nanomaterial synthesis; nanomaterials; non-thermal plasma; plasma; plasma liquid Interactions.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The synergistic relationship among plasmas, nanomaterials and their biomedical applications.
Figure 2
Figure 2
Typical structures of non-thermal DBD plasma and plasma jet devices at atmospheric pressure. (a) Surface DBD plasma; (b) FE-DBD plasma; and (c) plasma jet.
Figure 3
Figure 3
Possible reaction channels of plasma/gas–liquid interactions. With permission from Ref. [26] Copyright 2011 Wiley (Plasma Processes and Polymers 2011, 8, 904–913, DOI: 10.1002/ppap.201000099).
Figure 4
Figure 4
Plasma as reliable and safe therapeutic device for biomedical applications. For safe plasma clinical application, plasma devices and in vitro biological effects must be optimized.
Figure 5
Figure 5
A schematic illustration of the metal ion reduction, diffusion and nucleation at the plasma-liquid interface. The reduction reactions can occur in liquid medium by either solvated plasma-induced electron or plasma induced reactive species.

References

    1. Kong M.G., Keidar M., Ostrikov K. Plasmas meet nanoparticles-where synergies can advance the frontier of medicine. J. Phys. D Appl. Phys. 2011;44 doi: 10.1088/0022-3727/44/17/174018. - DOI
    1. Eliasson B., Kogelschatz U. Nonequilibrium volume plasma chemical processing. IEEE Trans. Plasma Sci. 1991;19:1063–1077. doi: 10.1109/27.125031. - DOI
    1. Eliasson B., Kogelschatz U. Modeling and applications of silent discharge plasmas. IEEE Trans. Plasma Sci. 1991;19:309–323. doi: 10.1109/27.106829. - DOI
    1. Li Y., Kang M.H., Uhm H.S., Lee G.J., Choi E.H., Han I. Effects of atmospheric-pressure non-thermal bio-compatible plasma and plasma activated nitric oxide water on cervical cancer cells. Sci. Rep. 2017;7:1–9. doi: 10.1038/srep45781. - DOI - PMC - PubMed
    1. Fridman G., Peddinghaus M., Ayan H., Fridman A., Balasubramanian M., Gutsol A., Brooks A., Friedman G. Blood coagulation and living tissue sterilization by floating-electrode dielectric barrier discharge in air. Plasma Chem. Plasma Process. 2006;26:425–442. doi: 10.1007/s11090-006-9024-4. - DOI

LinkOut - more resources