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. 2019 Jun;34(6):567-577.
doi: 10.1007/s10654-019-00481-x. Epub 2019 Jan 16.

Hospitalisation of people with dementia: evidence from English electronic health records from 2008 to 2016

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Hospitalisation of people with dementia: evidence from English electronic health records from 2008 to 2016

Andrew Sommerlad et al. Eur J Epidemiol. 2019 Jun.

Abstract

Hospitalisation of people with dementia is associated with adverse outcomes and high costs. We aimed to examine general, i.e. non-psychiatric, hospitalisation rates, changes since 2008 and factors associated with admission. We also aimed to compare admission rates of people with dementia with age-matched people without dementia. We conducted a cohort study of adults ≥ 65 years, with dementia diagnosed during the 2008-2016 study window, derived from a large secondary mental healthcare database in South London, UK. We used national general hospital records to identify emergency and elective hospitalisations. We calculated the cumulative incidence and rate of hospitalisation and examined predictors of hospitalisation using negative binomial regression, with multiple imputation for missing covariate data. We calculated age-standardised admission ratio for people with dementia compared to those without. Of 10,137 people, 50.6% were admitted to hospital in the year following dementia diagnosis and 75.9% were admitted during median 2.5 years follow-up. Annual admission rate was 1.26/person-year of which 0.90/person-year were in emergency. Emergency hospitalisation rate increased throughout the study period. Compared to controls without diagnosed dementia in the catchment area, the age-standardised emergency admission ratio for people with dementia was 2.06 (95% CI 1.95, 2.18). Male, older, white and socio-economically deprived people and those with clinically significant comorbid physical illness, depressed mood, activity of daily living or living condition problems had more hospitalisations. Emergency hospitalisations of people with dementia are higher than those without, and increasing. Many factors associated with admission are social and psychological, and may be targets for future interventions that aim to reduce avoidable admissions.

Keywords: Dementia; Geriatrics; Health services; Hospitalization; Prognosis.

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Conflict of interest statement

Conflict of interest

All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: AS reports funded a grant from the Wellcome trust, G Lewis reports a grant from University College London and G Livingston reports grants from Department of Health, National Institute for Health Research (Health Technology Assessment, Biomedical Research Centre, Efficacy and Mechanism Evaluation streams), Alzheimer society and the Economic and Social Research Council during the conduct of the study. RS reports grants from Janssen, Roche, and other financial relationships with GlaxoSmithKline outside the submitted work. No other relationships or activities that could appear to have influenced the submitted work.

Ethical approval

The Oxfordshire Research Ethics Committee C (reference 08/H0606/71 + 5) approved the mental health care records data resource (CRIS) for secondary analysis, including linked hospitalization data (HES). The terms of the ethical approval do not require consent to be provided but all participants have the right to opt out of data use at any time.

Figures

Fig. 1
Fig. 1
Distribution of count of general hospital admissions for people with dementia during first year after diagnosis (n = 10,137)

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