Gaining Weight: Insulin-Eating Islet Macrophages
- PMID: 30650372
- DOI: 10.1016/j.immuni.2018.12.026
Gaining Weight: Insulin-Eating Islet Macrophages
Abstract
The role of the immune system in homeostasis of pancreatic β cells in type 2 diabetes mellitus is poorly characterized. In a recent issue of Cell Metabolism, Ying et al. (2018) report that two subpopulations of macrophages expand during obesity to impair β cell function.
Copyright © 2018. Published by Elsevier Inc.
Comment on
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Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity.Cell Metab. 2019 Feb 5;29(2):457-474.e5. doi: 10.1016/j.cmet.2018.12.003. Epub 2018 Dec 27. Cell Metab. 2019. PMID: 30595478 Free PMC article.
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