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Comment
. 2019 Mar;21(2):296-298.
doi: 10.1017/cem.2018.482. Epub 2019 Jan 17.

Is an IOTA of evidence enough?

Seth Nicholas Phillips Davis  1 , Nina Di Nicola  1 , Sophie Gosselin  1
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Comment

Is an IOTA of evidence enough?

Seth Nicholas Phillips Davis et al. CJEM. 2019 Mar.

Abstract

Clinical questionDo patients with acute illness admitted to the hospital and treated with liberal oxygen therapy compared with those treated with conservative oxygen therapy have differences in mortality and morbidity?Article chosenChu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet 2018;391(10131):1693-705. OBJECTIVES: To analyse the existing literature to assess the potential benefits or harms of supplemental oxygen use in acutely ill patients.

Keywords: drug therapy; hyperoxemia; meta-analysis; oxygen therapy.

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