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Randomized Controlled Trial
. 2019 Jun;80(6):365-373.
doi: 10.1111/cod.13214. Epub 2019 Mar 15.

Effectiveness of a skin care programme for the prevention of contact dermatitis in healthcare workers (the Healthy Hands Project): A single-centre, cluster randomized controlled trial

Maryam Soltanipoor  1   2 , Sanja Kezic  1 , Judith K Sluiter  1 , Fleur de Wit  2 , Angela L Bosma  3 , Ruth van Asperen  2 , Thomas Rustemeyer  2
Affiliations
Randomized Controlled Trial

Effectiveness of a skin care programme for the prevention of contact dermatitis in healthcare workers (the Healthy Hands Project): A single-centre, cluster randomized controlled trial

Maryam Soltanipoor et al. Contact Dermatitis. 2019 Jun.

Abstract

Background: Healthcare workers (HCWs) are at risk of developing hand dermatitis (HD). Guidelines recommend moisturizers to prevent HD, but in practice their effectiveness has been poorly investigated.

Objectives: To assess whether an intervention aimed at improving skin care leads to a reduction in HD severity.

Methods: In this 1-year randomized controlled trial, 9 wards (285 HCWs) were allocated to an intervention group (IG), and 10 wards (216 HCWs) were allocated to the control group (CG). The intervention included provision of cream dispensers with electronic monitoring of use, regularly communicated to the HCWs. The primary and secondary outcomes were change from baseline in Hand Eczema Severity Index (HECSI) score (ΔHECSI) and change in natural moisturizing factor (NMF) level (ΔNMF).

Results: At 12 months, the rates of loss to follow-up were 41% and 39% in the IG and the CG, respectively. The HECSI score was reduced in the IG by -6.2 points (95%CI: -7.7 to -4.7) and in the CG by -4.2 points (95%CI: -6.0 to -2.4). There was no significant difference in ΔHECSI or ΔNMF between the groups. Relative improvement in the HECSI score was significantly higher in the IG than in the CG (56% vs 44%). In a subgroup of HCWs with mild HD, the IG showed a larger HECSI score decrease than the CG (P < 0.001).

Conclusion: Although there was no significant effect on the primary outcomes, the intervention showed overall positive effects on the HECSI score.

Keywords: hand dermatitis; hand moisturizers; healthcare; nurses; prevention.

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Conflict of interest statement

The PhD project of M. Soltanipoor was funded by an unrestricted grant from DEB Group Ltd, Denby, UK. DEB Group Ltd also funded the dispensers with study creams. The participants in the study were covered by their work insurance. The sponsor was not involved in the study design, execution of the trial, or writing study reports. The authors report no further conflicts of interest.

Figures

Figure 1
Figure 1
Flow diagram of wards and employees included in the Healthy Hands Project randomized controlled trial. HCW, heathcare worker
See this image and copyright information in PMC

References

    1. Belsito DV. Occupational contact dermatitis: etiology, prevalence, and resultant impairment/disability. J Am Acad Dermatol. 2005;53:303‐313. - PubMed
    1. van Gils RF, Boot CR, van Gils PF, et al. Effectiveness of prevention programmes for hand dermatitis: a systematic review of the literature. Contact Dermatitis. 2011;64:63‐72. - PubMed
    1. Visser MJ, Verberk MM, van Dijk FJ, Bakker JG, Bos JD, Kezic S. Wet work and hand eczema in apprentice nurses; part I of a prospective cohort study. Contact Dermatitis. 2014;70:44‐55. - PubMed
    1. Ibler KS, Jemec GB, Agner T. Exposures related to hand eczema: a study of healthcare workers. Contact Dermatitis. 2012;66:247‐253. - PubMed
    1. Stocks SJ, McNamee R, Turner S, Carder M, Agius RM. The impact of national‐level interventions to improve hygiene on the incidence of irritant contact dermatitis in healthcare workers: changes in incidence from 1996 to 2012 and interrupted times series analysis. Br J Dermatol. 2015;173:165‐171. - PubMed

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