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. 2019 Feb 1;117(1):e63-e67.
doi: 10.5546/aap.2019.e63.

[Dengue outbreak in Buenos Aires, Argentina, 2016: Clinical and hematological features in children]

[Article in Spanish]
Claudia I Cazes  1 , Carolina M Carballo  2 , María L Praino  2 , Fausto M Ferolla  2 , Alicia Mistchenko  3 , María M Contrini  2 , Aurelia Fallo  2 , Eduardo L López  2
Affiliations
Free article

[Dengue outbreak in Buenos Aires, Argentina, 2016: Clinical and hematological features in children]

[Article in Spanish]
Claudia I Cazes et al. Arch Argent Pediatr. .
Free article

Abstract
in English, Spanish

Dengue is the human arbovirus with the highest morbidity and mortality in the world. The largest outbreak of dengue in Buenos Aires, Argentina, occurred during 2016.

Objective: To describe clinical and hematological features in children with confirmed dengue infection.

Methods: Cross sectional study that included children attended since January 18th to April 15th 2016 at Hospital de Niños "Dr. Ricardo Gutiérrez".

Results: among 156 registered cases, 82 confirmed cases by virology test; 130 (83 %) autochthonous cases. The most frequent clinical manifestations were fever, headache and retro-ocular pain. Laboratory abnormalities were leukopenia, thrombocytopenia and increased liver enzymes. Thirty-five children were hospitalized (23 %), 25 (16 %) with warning signs. In our study, no cases of severe dengue occurred.

Conclusions: early recognition of warning signs and hematological monitoring is essential in order to detect patients at risk and offer them adequate early treatment.

El dengue es la arbovirosis humana que más morbimortalidad ocasiona mundialmente. Durante 2016, se registró, en la Ciudad de Buenos Aires, Argentina, la mayor epidemia de esta enfermedad. Objetivo: describir las características clínicas y hematológicas en una población pediátrica. Métodos: estudio de corte transversal que incluyó a pacientes atendidos del 18-1-16 al 15-4-16 en el Hospital de Niños "Dr. Ricardo Gutiérrez". Resultados: se registraron 156 casos, 82 confirmados por virología; 130 (83 %), autóctonos. Las manifestaciones clínicas más frecuentes fueron fiebre, cefalea y dolor retroocular. Las alteraciones del laboratorio significativas fueron leucopenia, plaquetopenia y aumento de transaminasas. Se internaron 35 pacientes (23 %), 25 (16 %) con signos de alarma. No se presentó ningún caso de dengue grave. Conclusiones: el reconocimiento oportuno de los signos de alarma y el control hematológico resultan fundamentales para detectar a los niños en riesgo y ofrecerles tratamiento de soporte en forma precoz.

Keywords: dengue virus, child, pediatric.

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