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. 2018 Nov-Dec;33(6):579-587.
doi: 10.21470/1678-9741-2018-0106.

The Importance of Intra-aortic Pulse Pressure After Anterior ST-segment Elevation Myocardial Infarction

Ilker Gul  1 , Levent Cerit  1 , Bihter Senturk  2 , Mustafa Beyazıt Alkan  3 , Hatice Kemal  1 , Zeynep Cerit  4 , Belma Yaman  1 , Songul Usalp  1 , Hamza Duygu  1
Affiliations

The Importance of Intra-aortic Pulse Pressure After Anterior ST-segment Elevation Myocardial Infarction

Ilker Gul et al. Braz J Cardiovasc Surg. 2018 Nov-Dec.

Abstract

Objective: To evaluate the association of pulse pressure (PP) with mortality and major adverse cardiac events (MACE) in one-year period after anterior ST-elevation myocardial infarction (A-STEMI).

Methods: A total of 261 consecutive patients whose blood pressure was measured with the aid of a catheter before primary percutaneous coronary intervention (PPCI) between August 2016 and February 2017 were included in the study. The patients were divided into three groups according to pulse pressure (PP) (Group 1, PP<35 mmHg; Group 2, 35≤PP≤50 mmHg; Group 3, PP>50 mmHg).

Results: The mean age of the patients was 63.4±14.1 years, and 206 of them were male. The groups were similar in terms of age and diastolic blood pressure (DBP). The ratio of female patients in Group 1 was higher, and their systolic blood pressure (SBP) was lower than those from the other groups (P=0.005 vs. P=0.042). The rates of MACE and mortality were higher in Group 1. The predictive PP values were calculated to be 42.5 mmHg for development of MACE and 41.5 mmHg for mortality. One-year survival ratio was worse in Group 1 than in the others according to Kaplan-Meier analysis (P<0.001).

Conclusion: The values of PP which was measured intra-aortically in patients with A-STEMI were associated with mortality and MACE in the one-year follow-up period.

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Conflict of interest statement

No conflict of interest.

Figures

Fig. 1
Fig. 1
Distribution of patients with major adverse cardiac events (MACE) during one-year follow-up according to the study groups.
Fig. 2
Fig. 2
The pulse pressure value which can predict the occurrence of mortality during one-year follow-up was determined as 41.5 mmHg in receiver operating characteristics analysis. AUC=area under the curve
Fig. 3
Fig. 3
The pulse pressure value which can predict the occurrence of major adverse cardiac events (MACE) rates during one-year follow-up was determined as 42.5 mmHg in receiver operating characteristics analysis. AUC=area under the curve
Fig. 4
Fig. 4
One-year survival rate in Group 1 was detected lower than in other groups in Kaplan-Meier survival analysis. Cum=cumulative; PP=pulse pressure; PPR=pulse pressure ratio
See this image and copyright information in PMC

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