[Sterile eosinophilic pustulosis (Ofuji)]

Abstract

In recent years there has been an increase in the information available on "eosinophilic pustular folliculitis (Ofuji)". A significant feature of this disease is extensive tissue eosinophilia in association with follicular, intraepidermal or subcorneal pustules containing eosinophils. A review of the current literature reveals that the skin lesions vary widely. Some patients present with pustules on an erythematous base; in others, annular or circinate papulonodular lesions predominate, which may become crusted. Even vesicular lesions have been reported. The extensive tissue eosinophilia itself suggests that the condition is not caused by an exogenous infectious agent. Most data implicate an immunopathological event that is still not well understood.