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Review
. 2019 Apr;47(2):98-107.
doi: 10.1249/JES.0000000000000184.

Considering Type 1 Diabetes as a Form of Accelerated Muscle Aging

Cynthia M F Monaco  1 , Molly A Gingrich, Thomas J Hawke
Affiliations
Review

Considering Type 1 Diabetes as a Form of Accelerated Muscle Aging

Cynthia M F Monaco et al. Exerc Sport Sci Rev. 2019 Apr.

Abstract

Recent evidence reveals impairments to skeletal muscle health in adolescent/young adults with type 1 diabetes (T1D). Interestingly, the observed changes in T1D are not unlike aged muscle, particularly, the alterations to mitochondria. Thus, we put forth the novel hypothesis that T1D may be considered a condition of accelerated muscle aging and that, similar to aging, mitochondrial dysfunction is a primary contributor to this complication.

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