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Review
. 2019 Aug;124(2):221-241.
doi: 10.1111/bju.14681. Epub 2019 Feb 5.

Consensus statements on the management of clinically localized prostate cancer from the Hong Kong Urological Association and the Hong Kong Society of Uro-Oncology

Wai-Kit Ma  1 , Darren Ming-Chun Poon  2 , Chi-Kwok Chan  3 , Tim-Wai Chan  4 , Foon-Yiu Cheung  5 , Lap-Yin Ho  6 , Eric Ka-Chai Lee  7 , Angus Kwong-Chuen Leung  8 , Simon Yiu-Lam Leung  9 , Hing-Shing So  10 , Po-Chor Tam  11 , Philip Wai-Kay Kwong  12
Affiliations
Review

Consensus statements on the management of clinically localized prostate cancer from the Hong Kong Urological Association and the Hong Kong Society of Uro-Oncology

Wai-Kit Ma et al. BJU Int. 2019 Aug.

Abstract

Objective: To formulate consensus statements to facilitate physician management strategies for patients with clinically localized prostate cancer (PCa) in Hong Kong by jointly convening a panel of 12 experts from the two local professional organizations representing PCa specialists, who had previously established consensus statements on the management of metastatic PCa for the locality.

Methods: Through a series of meetings, the panellists discussed their clinical experience and the published evidence regarding various areas of the management of localized PCa, then drafted consensus statements. At the final meeting, each drafted statement was voted on by every panellist based on its practicability of recommendation in the locality.

Results: A total of 76 consensus statements were ultimately accepted and established by panel voting.

Conclusion: Derived from the recent evidence and major overseas guidelines, along with local clinical experience and practicability, the consensus statements were aimed to serve as a practical reference for physicians in Hong Kong for the management of localized PCa.

Keywords: #PCSM; #ProstateCancer; Hong Kong; consensus; localized prostate cancer; male.

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Conflict of interest statement

None declared. Conflict of interest statements from all panellists are listed in Appendix S3.

Figures

Figure 1
Figure 1
Diagnostic evaluation and staging for suspicious localized prostate cancer (PCa). *Free/total (f/t) PSA ratio or prostate health index (PHI) may aid counselling for the decision on whether to perform a prostate biopsy. † TRUS‐guided biopsy with 10–12 cores is recommended. ‡Multiparametric (mp)MRI or combination of systematic and MRI‐targeted biopsies (either with cognitive guidance or mpMRI/ultrasonography fusion) can be offered. ISUP, International Society of Urological Pathology; PET, positron emission tomography; PSMA, prostate‐specific membrane antigen.
Figure 2
Figure 2
Localized prostate cancer treatment algorithm. *Offer to patients not eligible for local curative treatment (e.g. poor premorbid status) and those with a short life expectancy (<10 years). †Offer to patients with a low risk of extracapsular disease (based on nomograms). ‡Offer when the estimated risk of lymph node metastasis is >5% based on nomograms. §With consideration of the patient's history, functional status, values and preferences, and his tolerance for the potential toxicities and impact of radiotherapy ( RT) on quality of life. ADT, androgen deprivation therapy; EBRT, external beam radiation therapy; ePLND, extended pelvic lymph node dissection; RP, radical prostatectomy.
See this image and copyright information in PMC

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