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Review
. 2019 Jan 16;101(2):204-206.
doi: 10.1016/j.neuron.2018.12.027.

Crosstalk of Local Translation and Mitochondria: Powering Plasticity in Axons and Dendrites

Wilfried Rossoll  1 , Gary J Bassell  2
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Free article
Review

Crosstalk of Local Translation and Mitochondria: Powering Plasticity in Axons and Dendrites

Wilfried Rossoll et al. Neuron. .
Free article

Abstract

Two papers in Cell uncover reciprocal crosstalk of local translation and mitochondria in neurons. Rangaraju et al. (2019) observe tethered compartments of stable mitochondria in dendrites that provide a local energy supply for mRNA translation at synapses. Cioni et al. (2019) report a novel association of axonal RNA granules with Rab7a-late endosomes that provides a platform for local translation supporting mitochondria.

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