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Review
. 2019 Jan 16;24(2):314.
doi: 10.3390/molecules24020314.

Chiral Derivatives of Xanthones with Antimicrobial Activity

Joana Araújo  1 , Carla Fernandes  2   3 , Madalena Pinto  4   5 , Maria Elizabeth Tiritan  6   7   8
Affiliations
Review

Chiral Derivatives of Xanthones with Antimicrobial Activity

Joana Araújo et al. Molecules. .

Abstract

According to the World Health Organization, the exacerbated use of antibiotics worldwide is increasing multi-resistant infections, especially in the last decade. Xanthones are a class of compounds receiving great interest in drug discovery and development that can be found as natural products or obtained by synthesis. Many derivatives of xanthones are chiral and associated with relevant biological activities, including antimicrobial. The aim of this review is to compile information about chiral derivatives of xanthones from natural sources and their synthesized examples with antimicrobial activity.

Keywords: antimicrobial; caged xanthones; chiral derivatives of xanthones; chirality; xanthones.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Xanthone scaffold.
See this image and copyright information in PMC

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