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. 2018 Nov 29;18(1):7-16.
doi: 10.1002/rmb2.12258. eCollection 2019 Jan.

Assisted reproductive technology in Japan: A summary report for 2016 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Osamu Ishihara  1 , Seung Chik Jwa  1 , Akira Kuwahara  2 , Tomonori Ishikawa  3 , Koji Kugu  4 , Rintaro Sawa  5   6 , Kouji Banno  7 , Minoru Irahara  2 , Hidekazu Saito  8
Affiliations

Assisted reproductive technology in Japan: A summary report for 2016 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Osamu Ishihara et al. Reprod Med Biol. .

Abstract

Purpose: The Japan Society of Obstetrics and Gynecology started an online cycle-based assisted reproductive technology (ART) registry system in 2007. This report presents the characteristics and treatment outcomes of ART registered for the cycles practiced during 2016.

Methods: Cycle-specific information for all ART cycles implemented in participating ART facilities were collected. A descriptive analysis was conducted for the registry database of 2016.

Results: In total, 447 790 treatment cycles and 54 110 neonates (one in 18.1 neonates born in Japan) were reported in 2016. The mean patients' age was 38.1 years (SD = 4.5). Among the egg retrieval cycles, 104 575 of 251 399 (41.6%) were freeze-all cycles without fresh embryo transfers (ET), while fresh ET was performed in 64 497 cycles (58.4%). A total of 187 132 frozen-thawed ET cycles were reported, resulting in 62 432 pregnancies and 44 484 neonates born. Single ET was selected for 81.0% of fresh transfers and 82.7% of frozen cycles, resulting in singleton pregnancy/live birth rates of 97.0%/96.4% and 96.7%/96.4%, respectively.

Conclusion: The total ART cycles and subsequent live births continued to increase in 2016. Single ET was performed more than 80%, and ET has shifted from using fresh embryos to frozen ones.

Keywords: ART registry; Japan Society of Obstetrics and Gynecology; freeze‐all; in vitro fertilization; single embryo transfer.

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Figures

Figure 1
Figure 1
Age distributions of registered cycles, different subgroup of cycles with ET, pregnancy, and live birth. Adapted from the Japan Society of Obstetrics and Gynecology assisted reproductive technology Databook 2016 (http://plaza.umin.ac.jp/~jsogart/2016data_20180930.pdf). ET, embryo transfer
Figure 2
Figure 2
Pregnancy, live birth, and miscarriage rates according to patients’ age. Adapted from the Japan Society of Obstetrics and Gynecology assisted reproductive technology Databook 2016 (http://plaza.umin.ac.jp/~jsog-art/2016data_20180930.pdf). ET, embryo transfer
See this image and copyright information in PMC

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