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Case Reports
. 2019 Jan 8:15:e00489.
doi: 10.1016/j.idcr.2019.e00489. eCollection 2019.

Spontaneous pneumococcal peritonitis diagnosed by qPCR

Daniel Jarovsky  1 , Thais Grodzicki Ambrus  1 , Mariana Galvão Gurgel  1 , Marcelo Jenné Mimica  1 , Mariana Volpe Arnoni  2 , Flávia Jacqueline Almeida  1 , Marco Aurélio Palazzi Sáfadi  1 , Eitan Naaman Berezin  1
Affiliations
Case Reports

Spontaneous pneumococcal peritonitis diagnosed by qPCR

Daniel Jarovsky et al. IDCases. .

Abstract

Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with prior or concurrent antimicrobial use. DNA amplification detects very few copies of target DNA under ideal conditions in CSF or pleural effusion and, therefore, can be useful in selected infections. A culture-negative spontaneous pneumococcal peritonitis without preexisting peritoneal disease diagnosed by qPCR is herein described.

Keywords: Invasive pneumococcal disease; Real-time PCR; Spontaneous peritonitis; Streptococcus pneumoniae; lytA primer.

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Figures

Fig. 1
Fig. 1
Exploratory laparotomy revealing dilated and inflamed small bowel and purulent secretions in the abdominal cavity.
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