Hepatocyte-specific and extra-hepatocyte actions of perilipin-2 during fatty liver disease: benefits of being extra

Lindsey Kennedy¹, Heather Francis^{2

1}, Gianfranco Alpini^{2

1}

Affiliations

¹ Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
² Research, Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA.

Comment

Lindsey Kennedy et al. J Physiol. 2019 Mar.

. 2019 Mar;597(6):1431-1432.

doi: 10.1113/JP277539. Epub 2019 Jan 29.

Lindsey Kennedy¹, Heather Francis^{2

1}, Gianfranco Alpini^{2

1}

¹ Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
² Research, Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA.

No abstract available

Keywords: NAFLD; NASH; Perilipin-2; Steatosis.

Comment on

Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions.
Orlicky DJ, Libby AE, Bales ES, McMahan RH, Monks J, La Rosa FG, McManaman JL. Orlicky DJ, et al. J Physiol. 2019 Mar;597(6):1565-1584. doi: 10.1113/JP277140. Epub 2019 Jan 2. J Physiol. 2019. PMID: 30536914 Free PMC article.

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1. Orlicky DJ, Libby AE, Bales ES, McMahan RH, Monks J, La Rosa FG & McManaman JL (2019). Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions. J Physiol 597, 1565–1584. - PMC - PubMed