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Review
. 2019;15(1):47-52.
doi: 10.2174/1573396315666190118101953.

Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update

Affiliations
Review

Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update

Despoina Gkentzi et al. Curr Pediatr Rev. 2019.

Abstract

Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly prescribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inappropriately with various short and long-term effects. The rational use of antimicrobials is of paramount importance in this population and structured antimicrobial stewardship interventions should be in place. These interventions are slightly different from those used in adults and older children due to the particularities of the neonatal medicine. The aim of this review is to provide an update in the field and identify areas for further consideration and future research.

Keywords: Antimicrobial stewardship; Candida; interventions; neonate; pathogens; therapeutic challenges..

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References

    1. Antimicrobial resistance: Global report on surveillance 2014. WHO2014; Available from: http://www.who.int/drugresistance/ documents/surveillancereport/en/
    1. Bell B.G., Schellevis F., Stobberingh E., Goossens H., Pringle M. A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance. BMC Infect. Dis. 2014;14:13. - PMC - PubMed
    1. Tzialla C., Borghesi A., Serra G., Stronati M., Corsello G. Antimicrobial therapy in neonatal intensive care unit. Ital. J. Pediatr. 2015;41:27. - PMC - PubMed
    1. Cantey J.B., Wozniak P.S., Sanchez P.J. Prospective surveillance of antibiotic use in the neonatal intensive care unit: results from the SCOUT study. Pediatr. Infect. Dis. J. 2015;34(3):267–272. - PubMed
    1. Cotten C.M., McDonald S., Stoll B., et al. The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants. Pediatrics. 2006;118(2):717–722. - PubMed

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