Imaging the term neonatal brain
- PMID: 30657135
- PMCID: PMC6054233
- DOI: 10.1093/pch/pxx161
Imaging the term neonatal brain
Abstract
Brain imaging is important for the diagnosis and management of sick term neonates. Although ultrasound and computed tomography may provide some information, magnetic resonance imaging is now the brain imaging modality of choice because it is the most sensitive technique for detecting and quantifying brain abnormalities and does not expose infants to radiation. This statement describes the principles, roles and limitations of these three imaging modalities and makes recommendations for appropriate use in term neonates. The primary focus is the brain of term infants with neonatal encephalopathy, many of whom are diagnosed with hypoxic-ischemic encephalopathy.
Keywords: Brain imaging; Encephalopathy; Newborn.
Similar articles
-
Implementation of Neonatal Neurocritical Care Program Improved Short-Term Outcomes in Neonates With Moderate-to-Severe Hypoxic Ischemic Encephalopathy.Pediatr Neurol. 2019 Dec;101:64-70. doi: 10.1016/j.pediatrneurol.2019.02.023. Epub 2019 Mar 11. Pediatr Neurol. 2019. PMID: 31047757
-
Diffusion tensor imaging assesses white matter injury in neonates with hypoxic-ischemic encephalopathy.Neural Regen Res. 2017 Apr;12(4):603-609. doi: 10.4103/1673-5374.205102. Neural Regen Res. 2017. PMID: 28553341 Free PMC article.
-
[Early assessment of severe hypoxic-ischemic encephalopathy in neonates by diffusion-weighted magnetic resonance imaging techniques and its significance].Zhonghua Er Ke Za Zhi. 2007 Nov;45(11):843-7. Zhonghua Er Ke Za Zhi. 2007. PMID: 18282417 Chinese.
-
Neonatal Hypoxic-ischemic Encephalopathy: A Radiological Review.J Pediatr Neurosci. 2017 Jan-Mar;12(1):1-6. doi: 10.4103/1817-1745.205646. J Pediatr Neurosci. 2017. PMID: 28553370 Free PMC article. Review.
-
Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia.Pediatr Res. 2017 Jan;81(1-2):150-155. doi: 10.1038/pr.2016.195. Epub 2016 Sep 27. Pediatr Res. 2017. PMID: 27673422 Review.
Cited by
-
Subgaleal hemorrhage in neonates: a comprehensive review and summary recommendations.J Perinatol. 2025 Feb;45(2):167-179. doi: 10.1038/s41372-024-02116-w. Epub 2024 Sep 16. J Perinatol. 2025. PMID: 39284927 Review.
-
Subcortical brain volumes in neonatal hypoxic-ischemic encephalopathy.Pediatr Res. 2023 Nov;94(5):1797-1803. doi: 10.1038/s41390-023-02695-y. Epub 2023 Jun 23. Pediatr Res. 2023. PMID: 37353661
-
Methods for Monitoring Risk of Hypoxic Damage in Fetal and Neonatal Brains: A Review.Fetal Diagn Ther. 2022;49(1-2):1-24. doi: 10.1159/000520987. Epub 2021 Dec 6. Fetal Diagn Ther. 2022. PMID: 34872080 Free PMC article. Review.
-
Discussing brain magnetic resonance imaging results for neonates with hypoxic-ischemic encephalopathy treated with hypothermia: A challenge for clinicians and parents.eNeurologicalSci. 2022 Sep 11;29:100424. doi: 10.1016/j.ensci.2022.100424. eCollection 2022 Dec. eNeurologicalSci. 2022. PMID: 36147866 Free PMC article.
-
Development and characterization of transfontanelle photoacoustic imaging system for detection of intracranial hemorrhages and measurement of brain oxygenation: Ex-vivo.Photoacoustics. 2023 Jul 27;32:100538. doi: 10.1016/j.pacs.2023.100538. eCollection 2023 Aug. Photoacoustics. 2023. PMID: 37575972 Free PMC article.
References
-
- Volpe JJ. Neonatal encephalopathy: An inadequate term for hypoxic-ischemic encephalopathy. Ann Neurol 2012;72(2):156–66. - PubMed
-
- Ment LR, Bada HS, Barnes P, et al. . Practice parameter: Neuroimaging of the neonate: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2002;58(12):1726–38. - PubMed
-
- Daneman A, Epelman M, Blaser S, Jarrin JR. Imaging of the brain in full-term neonates: Does sonography still play a role?Pediatr Radiol 2006;36(7):636–46. - PubMed
-
- van Wezel-Meijler G, Steggerda SJ, Leijser LM. Cranial ultrasonography in neonates: Role and limitations. Semin Perinatol 2010;34(1):28–38. - PubMed
-
- Chau V, Poskitt KJ, Sargent MA, et al. . Comparison of computer tomography and magnetic resonance imaging scans on the third day of life in term newborns with neonatal encephalopathy. Pediatrics 2009;123(1):319–26. - PubMed
Publication types
LinkOut - more resources
Full Text Sources