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. 2019 Mar;23(3):602-608.
doi: 10.1007/s10461-018-02384-6.

Correlates of Fatigue Among South African Adolescents Living with HIV and Receiving Antiretroviral Therapy

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Correlates of Fatigue Among South African Adolescents Living with HIV and Receiving Antiretroviral Therapy

Bronwynè J Coetzee et al. AIDS Behav. 2019 Mar.

Abstract

Fatigue among adolescents living with HIV is poorly understood. In this study, we examined the relationships between fatigue and demographic and psychosocial variables to further the understanding of the symptom experience and associated factors. We recruited consecutive attenders at ART clinics in the Western Cape, South Africa (N = 134, age 11-18 years). Participants completed a battery of questionnaires including measures of fatigue, insomnia and mood disturbance. Just under a quarter (24.6%) of adolescents reported elevated levels of fatigue that affected their functioning. The linear combination of age, depression, and insomnia explained 40.6% of the variance in fatigue. Amongst adolescents with HIV, fatigue seems a problematic symptom associated with poor sleep and mood disturbance. Timely identification and management of these potentially disabling symptoms are needed to attain better health outcomes and retention in care in this group. Interventions aimed at ameliorating these symptoms are needed.

Keywords: Adolescent; Antiretroviral therapy; Fatigue; HIV; South Africa.

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Conflict of interest statement

Conflicts of interest: The authors declare that they have no conflict of interest.

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References

    1. Joint United Nations Programme on HIV/AIDS [UNAIDS] Ending the AIDS epidemic for adolescents, with adolescents UNAIDS 2016 | REFERENCE A practical guide to meaningfully engage adolescents in the AIDS response. Geneva: 2016. [Internet]. Available from: www.unaids.org/sites/default/files/media…/ending-AIDS-epidemic-adolescen....
    1. Montaner JSG, Lima VD, Harrigan PR, Lourenço L, Yip B, Nosyk B, et al. Expansion of HAART Coverage Is Associated with Sustained Decreases in HIV/AIDS Morbidity, Mortality and HIV Transmission: The “HIV Treatment as Prevention” Experience in a Canadian Setting. Sluis-Cremer N, editor. PLoS One. 2014 Feb 12;9(2):e87872. doi: 10.1371/journal.pone.0087872. [Internet] - DOI - PMC - PubMed
    1. Herbst AJ, Cooke GS, Bärnighausen T, KanyKany A, Tanser F, Newell M. Adult mortality and antiretroviral treatment roll-out in rural KwaZulu-Natal, South Africa. Bull World Health Organ. 2009 Oct 1;87(10):754–62. [Internet]. Available from: http://www.who.int/bulletin/volumes/87/10/08-058982.pdf. - PMC - PubMed
    1. Volberding PA, Deeks SG. Antiretroviral therapy and management of HIV infection. Lancet. 2010 Jul;376(9734):49–62. [Internet]. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673610606769. - PubMed
    1. Jong E, Oudhoff LA, Epskamp C, Wagener MN, van Duijn M, Fischer S, et al. Predictors and treatment strategies of HIV-related fatigue in the combined antiretroviral therapy era. AIDS. 2010 Jun;24(10):1387–405. [Internet]. Available from: https://insights.ovid.com/crossref?an=00002030-201006190-00001. - PubMed

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