Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

doi:10.1186/s13643-018-0930-3

. 2019 Jan 19;8(1):27.

doi: 10.1186/s13643-018-0930-3.

Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

Candyce Hamel¹, Eddy Lang^{2

3}, Kate Morissette⁴, Andrew Beck⁵, Adrienne Stevens⁵, Becky Skidmore⁵, Heather Colquhoun⁶, John LeBlanc⁷, Ainsley Moore^{8

9}, John J Riva^{8

9}, Brett D Thombs^{10

11}, Ian Colman¹², Sophie Grigoriadis^{13

14

15}, Stuart Gordon Nicholls¹⁶, Beth K Potter¹², Kerri Ritchie^{16

17

18}, Julie Robert¹⁹, Priya Vasa²⁰, Bianca Lauria-Horner²¹, Scott Patten²², Simone N Vigod^{13

15}, Brian Hutton^{5

12}, Beverley J Shea^{5

12}, Shamila Shanmugasegaram⁴, Julian Little¹², David Moher^{5

12

23}

Affiliations

¹ Knowledge Synthesis Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. cahamel@ohri.ca.
² University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
³ Alberta Health Services, Calgary, Alberta, Canada.
⁴ Public Health Agency of Canada, Ottawa, Ontario, Canada.
⁵ Knowledge Synthesis Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
⁶ Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Canada.
⁷ Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
⁸ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.
⁹ Department of Family Medicine, McMaster University, David Braley Health Sciences Centre, Hamilton, Canada.
¹⁰ Lady Davis Institute of the Jewish General Hospital, Montreal, Quebec, Canada.
¹¹ Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
¹² School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
¹³ Department of Psychiatry, University of Toronto, Toronto, Canada.
¹⁴ Sunnybrook Health Sciences Centre, Toronto, Canada.
¹⁵ Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
¹⁶ Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
¹⁷ School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.
¹⁸ Department of Psychology, The Ottawa Hospital, Ottawa, Ontario, Canada.
¹⁹ Patient representative, Ottawa, Ontario, Canada.
²⁰ Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
²¹ Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
²² Department of Community Health Services and Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

PMID: 30660183
PMCID: PMC6339426
DOI: 10.1186/s13643-018-0930-3

Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

Candyce Hamel et al. Syst Rev. 2019.

. 2019 Jan 19;8(1):27.

doi: 10.1186/s13643-018-0930-3.

Authors

Affiliations

¹ Knowledge Synthesis Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. cahamel@ohri.ca.
² University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
³ Alberta Health Services, Calgary, Alberta, Canada.
⁴ Public Health Agency of Canada, Ottawa, Ontario, Canada.
⁵ Knowledge Synthesis Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
⁶ Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Canada.
⁷ Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
⁸ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.
⁹ Department of Family Medicine, McMaster University, David Braley Health Sciences Centre, Hamilton, Canada.
¹⁰ Lady Davis Institute of the Jewish General Hospital, Montreal, Quebec, Canada.
¹¹ Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
¹² School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
¹³ Department of Psychiatry, University of Toronto, Toronto, Canada.
¹⁴ Sunnybrook Health Sciences Centre, Toronto, Canada.
¹⁵ Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
¹⁶ Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
¹⁷ School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.
¹⁸ Department of Psychology, The Ottawa Hospital, Ottawa, Ontario, Canada.
¹⁹ Patient representative, Ottawa, Ontario, Canada.
²⁰ Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
²¹ Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
²² Department of Community Health Services and Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

PMID: 30660183
PMCID: PMC6339426
DOI: 10.1186/s13643-018-0930-3

Abstract

Background: In 2018, the World Health Organization reported that depression is the most common cause of disability worldwide, with over 300 million people currently living with depression. Depression affects an individual's physical health and well-being, impacts psychosocial functioning, and has specific negative short- and long-term effects on maternal health, child health, developmental trajectories, and family health. The aim of these reviews is to identify evidence on the benefits and harms of screening for depression in the general adult population and in pregnant and postpartum women.

Methods: Search strategies were developed and tested through an iterative process by an experienced medical information specialist in consultation with the review team. We will search MEDLINE, Embase, PsycINFO, CINAHL, and the Cochrane Library, and a randomized controlled trial filter will be used. The general adult review will be an update of a systematic review previously used by the Canadian Task Force on Preventive Health Care for their 2013 guideline recommendation. The search strategy will be updated and will start from the last search date of the previous review (May 2012). The pregnant and postpartum review will be a de novo review with no date restriction. For both reviews, we will search for unpublished documents following the CADTH Grey Matters checklist and relevant websites. Titles and abstracts will be screened using the liberal accelerated method. Two reviewers will independently screen full-text articles for relevance using pre-specified eligibility criteria and assess the risk of bias of included studies using the Cochrane Risk of Bias tool. Outcomes of interest for the general adult population review include symptoms of depression or diagnosis of major depressive disorder, health-related quality of life, day-to-day functionality, lost time at work/school, impact on lifestyle behaviour, suicidality, false-positive result, labelling/stigma, overdiagnosis or overtreatment, and harms of treatment. Outcomes of interest for the pregnant and postpartum review include mental health outcomes (e.g. diagnosis of major depressive disorder), parenting outcomes (e.g. mother-child interactions), and infant outcomes (e.g. infant health and development).

Discussion: These two systematic reviews will offer informative evaluations of depression screening. The findings will be used by the Task Force to help develop guideline recommendations on depression screening in the general adult population and in pregnant and postpartum women in Canada.

Systematic review registration: PROSPERO (CRD42018099690).

Keywords: Adults; Depression; Postpartum; Pregnancy; Screening; Systematic review.

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Written informed consent to publish was obtained from the stakeholders who provided feedback on the protocol. A copy of the written consent is available for review by the Editors-in-Chief of this journal. The stakeholder feedback has been anonymized and included as Additional file 8.

Competing interests

DM is co-editor-in-chief, Systematic Reviews. BH has received consultancy fees from Cornerstone Research Group for methodologic advice related to systematic reviews and meta-analysis and is a member of the Editorial team for Systematic Reviews. SG has received personal fees from UpToDate, personal fees from Eli Lilly, personal fees from Psychotherapy to go, personal fees from Compendium of pharmaceuticals over the last year, outside the submitted work. SP was a co-investigator on a grant supported jointly by the University of Calgary Hotchkiss Brain Institute and Pfizer. BT has received funding from the Canadian Institutes of Health Research to conduct systematic reviews and meta-analyses on the effectiveness of depression screening and the accuracy of depression screening tools. The remaining authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

**Fig. 1**
Analytic framework for depression screening in the general adult population

**Fig. 2**
Analytic framework for depression screening in pregnant and postpartum women

See this image and copyright information in PMC

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References

1. Public Health Agency of Canada (PHAC) ARCHIVED: chapter 2: a report on mental illnesses in Canada – mood disorders. 2002.
1. Lam RW, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder. Can J Psychiatr. 2016;61(9):510–523. doi: 10.1177/0706743716659416. - DOI - PMC - PubMed
1. American Psychiatric Assoication . Diagnostic and statistical manual of mental disorders. 5. Washington, DC: American Psychiatric Publishing; 2013.
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1. Stewart DE, Vigod S. Postpartum depression. N. Engl. J. Med. 2016;375(22):2177–2186. doi: 10.1056/NEJMcp1607649. - DOI - PubMed

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[1] Public Health Agency of Canada (PHAC) ARCHIVED: chapter 2: a report on mental illnesses in Canada – mood disorders. 2002.

[2] Public Health Agency of Canada (PHAC) ARCHIVED: chapter 2: a report on mental illnesses in Canada – mood disorders. 2002.

[3] Lam RW, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder. Can J Psychiatr. 2016;61(9):510–523. doi: 10.1177/0706743716659416. - DOI - PMC - PubMed

[4] Lam RW, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder. Can J Psychiatr. 2016;61(9):510–523. doi: 10.1177/0706743716659416. - DOI - PMC - PubMed

[5] American Psychiatric Assoication . Diagnostic and statistical manual of mental disorders. 5. Washington, DC: American Psychiatric Publishing; 2013.

[6] American Psychiatric Assoication . Diagnostic and statistical manual of mental disorders. 5. Washington, DC: American Psychiatric Publishing; 2013.

[7] World Health Organization . The ICD-10 classification of mental and behavioural disorders. Geneva: Diagnostic criteria for research; 1992.

[8] World Health Organization . The ICD-10 classification of mental and behavioural disorders. Geneva: Diagnostic criteria for research; 1992.

[9] Stewart DE, Vigod S. Postpartum depression. N. Engl. J. Med. 2016;375(22):2177–2186. doi: 10.1056/NEJMcp1607649. - DOI - PubMed

[10] Stewart DE, Vigod S. Postpartum depression. N. Engl. J. Med. 2016;375(22):2177–2186. doi: 10.1056/NEJMcp1607649. - DOI - PubMed

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Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

Affiliations

Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

Authors

Affiliations

Abstract

Conflict of interest statement

Ethics approval and consent to participate

Consent for publication

Competing interests

Publisher’s Note

Figures

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Cited by

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Abstract

Conflict of interest statement

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