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Review
. 2020 Mar;45(3):100393.
doi: 10.1016/j.cpcardiol.2018.08.005. Epub 2018 Sep 14.

Modern Management of ST-Segment Elevation Myocardial Infarction

Jennifer Frampton, James T Devries, Terrence D Welch, Bernard J Gersh
Review

Modern Management of ST-Segment Elevation Myocardial Infarction

Jennifer Frampton et al. Curr Probl Cardiol. 2020 Mar.

Abstract

Disruption of intracoronary plaque with thrombus formation resulting in severe or total occlusion of the culprit coronary artery provides the pathophysiologic foundation for ST-segment elevation myocardial infarction (STEMI). Management of STEMI focuses on timely restoration of coronary blood flow along with antithrombotic therapies and secondary prevention strategies. The purpose of this review is to discuss the epidemiology, pathophysiology, and diagnosis of STEMI. In addition, the review will focus on guideline-directed therapy for these patients and review potential associated complications.

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