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. 2018 Dec 31;22(4):55-61.
doi: 10.20463/jenb.2018.0030.

Effects of diet before endurance exercise on hepcidin response in young untrained females

Nanako Hayashi, Aya Ishibashi, Kazushige Goto

Effects of diet before endurance exercise on hepcidin response in young untrained females

Nanako Hayashi et al. J Exerc Nutrition Biochem. .

Abstract

Purpose: We examined the effects of diet before endurance exercise on hepcidin response in young untrained females.

Methods: Ten young untrained females [age: 20.6 ± 0.8 y, height: 157.5 ± 1.0 cm, weight: 54.4 ± 1.5 kg, and maximal oxygen uptake (VO2max): 35.9 ± 1.1 mL/kg/min] were involved in two experimental conditions with a crossover design. The two conditions were separated by approximately 1 month, and each condition was performed during the follicular phase. Subjects completed 60 min of pedaling at 65% of VO2max after consuming a meal (FED) or not consuming a meal (CON). Blood samples were collected before, immediately after, and 3 h after exercise.

Results: Serum ferritin levels before exercise did not differ between the two conditions (P > 0.05). Blood glucose and lactate levels were significantly elevated immediately after exercise only under the FED condition (P < 0.05). Serum iron levels were significantly elevated after exercise under both conditions. However, the plasma interleukin-6 and serum hepcidin levels were not significantly different 3 h after exercise under either condition (P > 0.05).

Conclusion: Consuming a meal before endurance exercise at moderate intensity did not affect exercise-induced hepcidin elevation in young untrained females.

Keywords: Iron metabolism.

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Figures

Figure 1.
Figure 1.. Overview of the experiment on the testing day.
Figure 2.
Figure 2.. Blood glucose and lactate levels before and after exercise. Values are means ± SE. *; P < 0.05 vs. before †; P < 0.05 (FED vs. CON).
Figure 3.
Figure 3.. Serum iron levels before and after exercise. Values are means ± SE. *; P < 0.05 vs. before.
Figure 4.
Figure 4.. Plasma interleukin-6 (IL-6) levels before and after exercise. Values are means ± SE.
Figure 5.
Figure 5.. Serum hepcidin levels before and after exercise. Values are means ± SE.
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References

    1. Sinclar LM, Hinton PS. Prevalence of iron deficiency with and without anemia in recreationally active men and women. J Am Diet Assoc. 2005;105:975–8. - PubMed
    1. Babić Z, Papa B, Sikirika-Bosnjaković M, Prkacin I, Misigoj-Duraković M, Katicić M. Occult gastrointestinal bleeding in rugby players. J Sports Med Phy Fitness. 2001;41:399–402. - PubMed
    1. DeRuisseau KC, Cheuvront SN, Haymes EM, Sharp RG. Sweat iron and zinc losses during prolonged exercise. Int J Sport Nutr Exerc Metab. 2002;12:428–37. doi: 10.1123/ijsnem.12.4.428. - DOI - PubMed
    1. Lampe JW, Slavin JL, Apple FS. Poor iron status of women runners for marathon. Int J Sports Med. 1986;7:111–4. - PubMed
    1. Telford RD, Sly GJ, Hahn AG, Cunningham RB, Bryant C, Smith JA. Footstrike is the major causes of hemolysis during running. J Appl Physiol. 2003;94:38–42. doi: 10.1152/japplphysiol.00631.2001. - DOI - PubMed

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