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Review
. 2019 Mar;50(3):765-772.
doi: 10.1161/STROKEAHA.118.020379.

Genetics of Vascular Cognitive Impairment

Affiliations
Review

Genetics of Vascular Cognitive Impairment

Hugh S Markus et al. Stroke. 2019 Mar.
No abstract available

Keywords: atrophy; cerebral amyloid angiopathy; cerebral hemorrhage; magnetic resonance imaging; white matter.

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Figures

Fig 1
Fig 1. Typical Brain imaging appearances in CADASIL.
(A) Brain FLAIR MRI showing confluent white matter hyperintensities and lacunar infarcts. (B) Brain FLAIR MRI showing WMH involve the anterior temporal pole; this is a characteristic location for CADASIL. (C) Gradient echo MRI showing a microbleeds in the left thalamus.
Fig 2
Fig 2. CAA-related brain imaging findings.
(A) Axial computed tomography shows two intracerebral lobar haemorrhages in the same patients. Recurrent lobar bleeding occurred within 1 months. (B) Axial gradient echo (GRE) image shows multiple cerebral cortical microhaemorrhages. (C) Axial GRE sequence demonstrates cortical superficial siderosis characterized by curvilinear signal hypointensity following the gyral cortical surface. (D) Axial fluid attenuation inversion recovery (left) and GRE (right) images show non-traumatic convexity subarachnoid haemorrhage.

References

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