Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease
- PMID: 30661504
- PMCID: PMC6385587
- DOI: 10.1161/STROKEAHA.118.020482
Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease
Keywords: anemia; cerebrovascular circulation; hemolysis; hydroxyurea; oxygen consumption; stroke.
Figures
Similar articles
-
Sickle Cell Disease and Stroke.Pediatr Neurol. 2019 Jun;95:34-41. doi: 10.1016/j.pediatrneurol.2019.02.018. Epub 2019 Feb 27. Pediatr Neurol. 2019. PMID: 30948147 Review.
-
Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial.Blood. 2014 Aug 7;124(6):891-8. doi: 10.1182/blood-2013-12-545186. Epub 2014 Jun 9. Blood. 2014. PMID: 24914136 Free PMC article. Clinical Trial.
-
Preventing stroke in sickle cell anemia.N Engl J Med. 2005 Dec 29;353(26):2743-5. doi: 10.1056/NEJMp058274. N Engl J Med. 2005. PMID: 16382060 No abstract available.
-
Hydroxycarbamide treatment reduces transcranial Doppler velocity in the absence of transfusion support in children with sickle cell anaemia, elevated transcranial Doppler velocity, and cerebral vasculopathy: the EXTEND trial.Br J Haematol. 2021 Nov;195(4):612-620. doi: 10.1111/bjh.17698. Epub 2021 Jul 22. Br J Haematol. 2021. PMID: 34291449 Clinical Trial.
-
Neuroimaging in Sickle Cell Disease: A Review.J Neuroimaging. 2020 Nov;30(6):725-735. doi: 10.1111/jon.12766. Epub 2020 Aug 17. J Neuroimaging. 2020. PMID: 33463866 Review.
Cited by
-
Multi-center retrospective study of children with sickle cell disease admitted to pediatric intensive care units in the United States.Sci Rep. 2023 Apr 25;13(1):6758. doi: 10.1038/s41598-023-32651-z. Sci Rep. 2023. PMID: 37185357 Free PMC article.
-
Low Stroke Risk in Children With Sickle Cell Disease in French Guiana: A Retrospective Cohort Study.Front Med (Lausanne). 2022 Jun 28;9:851918. doi: 10.3389/fmed.2022.851918. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35836958 Free PMC article.
-
A case of Sβ+ sickle cell disease diagnosed in adulthood following acute stroke: it's 2021, are we there yet?J Community Hosp Intern Med Perspect. 2021 Sep 20;11(5):713-718. doi: 10.1080/20009666.2021.1954285. eCollection 2021. J Community Hosp Intern Med Perspect. 2021. PMID: 34567471 Free PMC article.
-
Vascular Instability and Neurological Morbidity in Sickle Cell Disease: An Integrative Framework.Front Neurol. 2019 Aug 13;10:871. doi: 10.3389/fneur.2019.00871. eCollection 2019. Front Neurol. 2019. PMID: 31474929 Free PMC article.
-
Choroid plexus perfusion in sickle cell disease and moyamoya vasculopathy: Implications for glymphatic flow.J Cereb Blood Flow Metab. 2021 Oct;41(10):2699-2711. doi: 10.1177/0271678X211010731. Epub 2021 Apr 28. J Cereb Blood Flow Metab. 2021. PMID: 33906512 Free PMC article.
References
-
- Ohene-Frempong K, Weiner SJ, Sleeper LA, Miller ST, Embury S, Moohr JW, et al. Cerebrovascular accidents in sickle cell disease: Rates and risk factors. Blood. 1998;91:288–294 - PubMed
-
- Schatz J, Finke RL, Kellett JM, Kramer JH. Cognitive functioning in children with sickle cell disease: A meta-analysis. J Pediatr Psychol. 2002;27:739–748 - PubMed
-
- Dowling MM, Kirkham FJ. Stroke in sickle cell anaemia is more than stenosis and thrombosis: The role of anaemia and hyperemia in ischaemia. Br J Haematol. 2017;176:151–153 - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical