[The recurrence of bladder cancer in the glans and fossa navicularis of urethra following cystectomy]

Abstract

A 42-year-old male was admitted to our Hospital. Diagnosis of invasive bladder cancer was made and a total cystectomy was carried out on September 14, 1982. Histological examination showed transitional cell carcinoma, grade II-III, pT2N0M0. After cystectomy, the patient was treated with a combination chemotherapy of cis-platinum, cyclophosphamide, adriamycin and 5-fluorouracil. After 3 years, he noticed an area of reddish and painless rashes around the urethral meatus. A biopsy of the skin lesion showed a nest formation of transitional cell carcinoma with lymphocyte infiltration under the squamous epithelium. A urethrectomy was carried out on January, 28, 1986. A histologic study established the diagnosis of recurrent transitional cell carcinoma. The pathological process seemed to be a result of hematogenous metastasis rather than multicentricity or implantation.