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Randomized Controlled Trial
. 2019 Mar;21(3):385-386.
doi: 10.1002/ejhf.1403. Epub 2019 Jan 22.

Potential role for interleukin-1 in the cardio-renal syndrome

Leo F Buckley  1 , Justin M Canada  2 , Salvatore Carbone  2 , Cory R Trankle  2 , Dinesh Kadariya  2 , Hayley Billingsley  2 , George F Wohlford  3 , Danielle L Kirkman  4 , Antonio Abbate  2 , Benjamin W Van Tassell  3
Affiliations
Randomized Controlled Trial

Potential role for interleukin-1 in the cardio-renal syndrome

Leo F Buckley et al. Eur J Heart Fail. 2019 Mar.
No abstract available

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Conflict of interest statement

Conflict of Interest: None.

Figures

Figure.
Figure.. Effects of Anakinra on C-Reactive Protein in Patients with Heart Failure and Chronic Kidney Disease
Anakinra reduced C-reactive protein in patients with heart failure and chronic kidney disease compared to placebo.
See this image and copyright information in PMC

References

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    1. Buckley LF, Abbate A. Interleukin-1 blockade in cardiovascular diseases: A clinical update. Eur Heart J 2018;39:2063–2069. - PubMed
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    1. Tassell BW Van, Canada J, Carbone S, Trankle C, Buckley L, Erdle CO, Abouzaki NA, Dixon D, Kadariya D, Christopher S, Schatz A, Regan J, Viscusi M, Buono M Del, Melchior R, Mankad P, Lu J, Sculthorpe R, Biondi-Zoccai G, Lesnefsky E,. Arena R, Abbate A. Interleukin-1 blockade in recently decompensated systolic heart failure: Results from REDHART (Recently Decompensated Heart Failure Anakinra Response Trial). Circ Hear Fail 2017;10:e004373. - PMC - PubMed

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