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. 2019 Jan 20;19(2):407.
doi: 10.3390/s19020407.

A Diagnostic Device for In-Situ Detection of Swine Viral Diseases: The SWINOSTICS Project

Concetta Montagnese  1 , Paolo Barattini  2 , Alessandro Giusti  3 , Gyula Balka  4 , Ugo Bruno  5 , Ioannis Bossis  6 , Athanasios Gelasakis  7 , Matteo Bonasso  8 , Panayiotis Philmis  9 , Lilla Dénes  10 , Sergio Peransi  11 , Manuel Rodrigo  12 , Santiago Simón  13 , Amadeu Griol  14 , Grzegorz Wozniakowski  15 , Katarzyna Podgorska  16 , Carolina Pugliese  17 , Lapo Nannucci  18 , Sabato D'Auria  19 , Antonio Varriale  20
Affiliations

A Diagnostic Device for In-Situ Detection of Swine Viral Diseases: The SWINOSTICS Project

Concetta Montagnese et al. Sensors (Basel). .

Abstract

In this paper, we present the concept of a novel diagnostic device for on-site analyses, based on the use of advanced bio-sensing and photonics technologies to tackle emerging and endemic viruses causing swine epidemics and significant economic damage in farms. The device is currently under development in the framework of the EU Commission co-funded project. The overall concept behind the project is to develop a method for an early and fast on field detection of selected swine viruses by non-specialized personnel. The technology is able to detect pathogens in different types of biological samples, such as oral fluids, faeces, blood or nasal swabs. The device will allow for an immediate on-site threat assessment. In this work, we present the overall concept of the device, its architecture with the technical requirements, and all the used innovative technologies that contribute to the advancements of the current state of the art.

Keywords: antibody; photonic integrated circuit (PIC); photonics; ring resonator; swine disease.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic representation of the target application of the SWINOSTICS (swine diseases field diagnostics toolbox) device. Three main steps are needed: sampling, analysis and virus detection.
Figure 2
Figure 2
Overall design and architecture scheme. Five separate functional modules compose the SWINOSTICS device: biosensor, optical analysis module, temperature conditioning module, bio-sensing surface regeneration and preservation module and finally process, control and communication module.
Figure 3
Figure 3
SEM images of silicon nitride grating coupler (left) and ring resonator (right).
Figure 4
Figure 4
Functionalized photonic integrated circuit (PIC) surface measurement (A) and regeneration step (B).
Figure 5
Figure 5
Main processing unit involved in the control and communication of the device.
Figure 6
Figure 6
Field application of the SWINOSTICS device. The device will work on the field (Pig farm, veterinary, etc.) and the data will be transferred trough the mobile app to the cloud system.
See this image and copyright information in PMC

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