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Comment
. 2019 Mar;9(3):313.
doi: 10.1158/2159-8290.CD-NB2019-004. Epub 2019 Jan 22.

Desmoid Tumors Respond to Sorafenib

No authors listed
Comment

Desmoid Tumors Respond to Sorafenib

No authors listed. Cancer Discov. 2019 Mar.

Abstract

A recent clinical trial shows that sorafenib is effective against desmoid tumors. The study found that 33% of tumors shrank in patients who received the drug. The estimated 1-year progression-free survival for the sorafenib-treated patients was 89%, and the 2-year rate was 81%.

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Comment on

  • Sorafenib for Advanced and Refractory Desmoid Tumors.
    Gounder MM, Mahoney MR, Van Tine BA, Ravi V, Attia S, Deshpande HA, Gupta AA, Milhem MM, Conry RM, Movva S, Pishvaian MJ, Riedel RF, Sabagh T, Tap WD, Horvat N, Basch E, Schwartz LH, Maki RG, Agaram NP, Lefkowitz RA, Mazaheri Y, Yamashita R, Wright JJ, Dueck AC, Schwartz GK. Gounder MM, et al. N Engl J Med. 2018 Dec 20;379(25):2417-2428. doi: 10.1056/NEJMoa1805052. N Engl J Med. 2018. PMID: 30575484 Free PMC article. Clinical Trial.

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