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Clinical Trial
. 1988 Jul-Aug;22(4):299-304.

[Use of prostacyclin in patients with ischemic stroke. A double-blind method II]

[Article in Polish]
J Huczyński  1 , R J Gryglewski, E Kostka-Trabka, A Dembińska-Kieć, E Pykosz-Mazur, W Sotowska, L Grodzińska, E Peczak, K Bieroń, A Kedzior, et al.
Affiliations
  • PMID: 3067105
Clinical Trial

[Use of prostacyclin in patients with ischemic stroke. A double-blind method II]

[Article in Polish]
J Huczyński et al. Neurol Neurochir Pol. 1988 Jul-Aug.

Abstract

Thirty patients with acute ischaemic stroke were allocated randomly into a group treated with prostacyclin and a group receiving placebo. The treatment was started 24 to 72 hours after the onset of stroke. Prostacyclin sodium (Wellcome, U.K. or Chinoin, HPR) or its solvent (glycine buffer) were administered intravenously once daily during 2 weeks in 6-hour infusions. Prostacyclin was infused at rates of 2.5-5.0 ng/kg/min. Statistically significant improvement appeared from the second day on in the prostacyclin group, and only from the eighth day on in the placebo group. However, the final improvement was not statistically different between these groups.

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