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Review
. 2018 Aug 9:6:Doc04.
doi: 10.3205/id000039. eCollection 2018.

Medical treatment for urogenital tuberculosis (UGTB)

Christian Wejse  1
Affiliations
Review

Medical treatment for urogenital tuberculosis (UGTB)

Christian Wejse. GMS Infect Dis. .

Abstract

Urogenital tuberculosis (UGTB) should in general be treated as pulmonary TB with a four-drug regimen of Isoniazid, Rifampicin, Ethambutol and Pyrazinamide for a total of 6 months, Ethambutol and Pyrazinamide only the first two months. Some patients may need longer treatment (cavitary disease, kidney abscess/malfunction, HIV co-infection). Treatment of multi-drug resistant tuberculosis (MDR-TB) requires use of long-term intravenous treatment with aminoglycosides and other drugs with considerable toxicity for 18-24 months. Complications such as urinary tract obstruction may occur and should be treated with corticosteroids or surgery.

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Figures

Table 1
Table 1. Treatment regimen for UGTB
Table 2
Table 2. Dose-reduction according to weight (adults <50 kg)
Table 3
Table 3. Drugs used for treatment of multi-drug resistant tuberculosis (MDR-TB)
Table 4
Table 4. Reduced kidney function (creatinin clearance
<30 ml/min); dose-reduction, adults
See this image and copyright information in PMC

References

    1. Gow JG, Barbosa S. Genitourinary tuberculosis. A study of 1117 cases over a period of 34 years. Br J Urol. 1984 Oct;56(5):449–455. - PubMed
    1. Cek M, Lenk S, Naber KG, Bishop MC, Johansen TE, Botto H, Grabe M, Lobel B, Redorta JP, Tenke P Members of the Urinary Tract Infection (UTI) Working Group of the European Association of Urology (EAU) Guidelines Office. EAU guidelines for the management of genitourinary tuberculosis. Eur Urol. 2005 Sep;48(3):353–362. doi: 10.1016/j.eururo.2005.03.008. - DOI - PubMed
    1. Kulchavenya E, Naber K, Bjerklund Johansen TE. Urogenital Tuberculosis: Classification, Diagnosis, and Treatment. Eur Urol Suppl. 2016 Jul;15(4):112–21. doi: 10.1016/j.eursup.2016.04.001. - DOI
    1. Chandra S, Chandra H, Chauhan N, Gaur DS, Gupta H, Pathak VP, Burathoki SK. Male genitourinary tuberculosis – 13 years experience at a tertiary care center in India. Southeast Asian J Trop Med Public Health. 2012 Mar;43(2):364–369. - PubMed
    1. World Health Organization. Global tuberculosis report 2017. Geneva: World Health Organization; 2017. Available from: http://www.who.int/tb/publications/global_report/en/