Microbiota in ICU, not only a gut problem

L Alagna¹, A Bandera^{2

3}, A Patruno⁴, A Muscatello², G Citerio^{4

5}, A Gori^{2

3}

Affiliations

¹ Infectious Diseases Unit, Departement of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. laura.alagna@policlinico.mi.it.
² Infectious Diseases Unit, Departement of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Department of Pathophysiology and Transplantation, School of Medicine and Surgery, University of Milan, Milan, Italy.
⁴ Neuro Intensive Care Unit, Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy.
⁵ School of Medicine and Surgery, University of University of Milan-Bicocca, Milan, Italy.

Comment

L Alagna et al. Intensive Care Med. 2019 May.

. 2019 May;45(5):733-737.

doi: 10.1007/s00134-018-05516-7. Epub 2019 Jan 22.

L Alagna¹, A Bandera^{2

3}, A Patruno⁴, A Muscatello², G Citerio^{4

5}, A Gori^{2

3}

¹ Infectious Diseases Unit, Departement of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. laura.alagna@policlinico.mi.it.
² Infectious Diseases Unit, Departement of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Department of Pathophysiology and Transplantation, School of Medicine and Surgery, University of Milan, Milan, Italy.
⁴ Neuro Intensive Care Unit, Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy.
⁵ School of Medicine and Surgery, University of University of Milan-Bicocca, Milan, Italy.

No abstract available

Comment on

Pathogen colonization of the gastrointestinal microbiome at intensive care unit admission and risk for subsequent death or infection.
Freedberg DE, Zhou MJ, Cohen ME, Annavajhala MK, Khan S, Moscoso DI, Brooks C, Whittier S, Chong DH, Uhlemann AC, Abrams JA. Freedberg DE, et al. Intensive Care Med. 2018 Aug;44(8):1203-1211. doi: 10.1007/s00134-018-5268-8. Epub 2018 Jun 23. Intensive Care Med. 2018. PMID: 29936583 Free PMC article.
The gut microbiota of critically ill patients: first steps in an unexplored world.
Ruppé É, Lisboa T, Barbier F. Ruppé É, et al. Intensive Care Med. 2018 Sep;44(9):1561-1564. doi: 10.1007/s00134-018-5309-3. Epub 2018 Jul 14. Intensive Care Med. 2018. PMID: 30008112 No abstract available.

Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients.
Gamage HKAH, Venturini C, Tetu SG, Kabir M, Nayyar V, Ginn AN, Roychoudhry B, Thomas L, Brown M, Holmes A, Partridge SR, Seppelt I, Paulsen IT, Iredell JR. Gamage HKAH, et al. Sci Rep. 2021 Mar 31;11(1):7252. doi: 10.1038/s41598-021-85946-4. Sci Rep. 2021. PMID: 33790304 Free PMC article.
Antimicrobial-associated harm in critical care: a narrative review.
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Gut microbiota alterations in critically ill older patients: a multicenter study.
Victoria M, Elena VB, Amparo GN, María JA, Adriana GV, Irene AC, Alejandra YM, Janeth BB, María AG. Victoria M, et al. BMC Geriatr. 2022 Apr 28;22(1):373. doi: 10.1186/s12877-022-02981-0. BMC Geriatr. 2022. PMID: 35484500 Free PMC article.