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. 2019 Feb;67(2):233-238.
doi: 10.4103/ijo.IJO_675_18.

Intermediate-term outcome of Aurolab aqueous drainage implant

Reji Philip  1 , Premanand Chandran  1 , Nabeed Aboobacker  1 , Mrunali Dhavalikar  1 , Ganesh V Raman  1
Affiliations

Intermediate-term outcome of Aurolab aqueous drainage implant

Reji Philip et al. Indian J Ophthalmol. 2019 Feb.

Abstract

Purpose: To report the intermediate-term safety and efficacy of Aurolab aqueous drainage implant (AADI) in patients with glaucoma.

Methods: Retrospective review of patients who underwent AADI between January 2013 and December 2016. Patients aged >16 years and with a minimum follow-up of 6 months were included. Success was defined as complete when the intraocular pressure was ≥6 and ≤21 mmHg without antiglaucoma medication and as qualified if those requiring additional antiglaucoma medications were included.

Results: The study included 55 patients (55 eyes) with a mean age ± standard deviation (SD) of 47.3 ± 18.1 years with a mean follow-up of 16.7 ± 11.4 months. Mean intraocular pressure reduced from 30.8 ± 11.1 mmHg to 13.1 ± 4.7, 14.1 ± 4.8, 15.7 ± 2.5 (P < 0.001) mmHg at 6 months, 1 year, and 2 years, respectively. The mean number of antiglaucoma medications reduced from 3.4 ± 1 to 0.8 ± 1.2, 0.7 ± 1.1, 0.8 ± 1 (P < 0.001) at 6 months, 1 year, and 2 years, respectively. The cumulative probability of complete and qualified success was 62% and 100% at 6 months, 54% and 92% at 1 year, and 43% and 88% at 2 years, respectively. Four patients failed during the follow-up period. Postoperative complication occurred in 28 eyes (51%), of which 17 eyes (31%) required intervention.

Conclusion: AADI is a safe and effective treatment for the control of intraocular pressure in patients with glaucoma.

Keywords: Adult glaucoma; Aurolab aqueous drainage implant; glaucoma drainage device.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Scatter plot showing the relationship between baseline intraocular pressure (IOP) and follow-up IOP at 6 months
Figure 2
Figure 2
Kaplan–Meier survival curve showing the cumulative probability of complete success
Figure 3
Figure 3
Kaplan–Meier survival curve showing the cumulative probability of qualified success
Figure 4
Figure 4
Scatter plot showing the relationship between preoperative best-corrected visual acuity (BCVA) and postoperative BCVA at 6 months
See this image and copyright information in PMC

Comment in

References

    1. Ramakrishnan R, Nirmalan PK, Krishnadas R, Thulasiraj RD, Tielsch JM, Katz J, et al. Glaucoma in a rural population of southern India: The Aravind comprehensive eye survey. Ophthalmology. 2003;110:1484–90. - PubMed
    1. Garudadri C, Senthil S, Khanna RC, Sannapaneni K, Rao HB. Prevalence and risk factors for primary glaucomas in adult urban and rural populations in the Andra Pradesh Eye Disease Study. Ophthalmology. 2010;117:1352–9. - PubMed
    1. Budenz DL, Barton K, Gedde SJ, Feuer WJ, Schiffman J, Costa VP, et al. Five-year treatment outcomes in the Ahmed Baerveldt comparison study. Ophthalmology. 2015;122:308–16. - PMC - PubMed
    1. Christakis PG, Kalenak JW, Tsai JC, Zurakowski D, Kammer JA, Harasymowycz PJ, et al. The Ahmed versus baerveldt study: Five-year treatment outcomes. Ophthalmology. 2016;123:2093–2102. - PubMed
    1. Kaushik S, Kataria P, Raj S, Pandav SS, Ram J. Safety and efficacy of a low-cost glaucoma drainage device for refractory childhood glaucoma. Br J Ophthalmol. 2017;0:1–5. - PubMed