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. 2019 Jan;19(1):51-63.
doi: 10.1080/15265161.2018.1544304.

Genomic Contextualism: Shifting the Rhetoric of Genetic Exceptionalism

Nanibaa' A Garrison  1 , Kyle B Brothers  2 , Aaron J Goldenberg  3 , John A Lynch  4
Affiliations

Genomic Contextualism: Shifting the Rhetoric of Genetic Exceptionalism

Nanibaa' A Garrison et al. Am J Bioeth. 2019 Jan.

Abstract

As genomic science has evolved, so have policy and practice debates about how to describe and evaluate the ways in which genomic information is treated for individuals, institutions, and society. The term genetic exceptionalism, describing the concept that genetic information is special or unique, and specifically different from other kinds of medical information, has been utilized widely, but often counterproductively in these debates. We offer genomic contextualism as a new term to frame the characteristics of genomic science in the debates. Using stasis theory to draw out the important connection between definitional issues and resulting policies, we argue that the framework of genomic contextualism is better suited to evaluating genomics and its policy-relevant features to arrive at more productive discussion and resolve policy debates.

Keywords: bioethics; genetic exceptionalism; genomic contextualism; stasis theory.

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References

    1. ACMG Board of Directors. 2015. ACMG policy statement: Updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing. Genet Med 17(1):68–69. - PubMed
    1. Arbour L, and Cook D. 2006. DNA on loan: Issues to consider when carrying out genetic research with aboriginal families and communities. Community Genet 9(3):153–160. doi:10.1159/000092651. - DOI - PubMed
    1. Aristotle. 1991. On rhetoric: a theory of civic discourse Translated by Kennedy GA Oxford, UK: Oxford University Press.
    1. Beauchamp TL, and Childress JF. 2013. Principles of biomedical ethics 7th ed. New York: Oxford University Press.
    1. Berg JS, Khoury MJ, and Evans JP. 2011. Deploying whole genome sequencing in clinical practice and public health: Meeting the challenge one bin at a time. Genetics in Medicine 13(6):499–504. doi:10.1097/GIM.0b013e318220aaba. - DOI - PubMed

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