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Review
. 2019 Jan 24;15(1):e1007480.
doi: 10.1371/journal.ppat.1007480. eCollection 2019 Jan.

Is the unique camouflage strategy of Pneumocystis associated with its particular niche within host lungs?

Philippe M Hauser  1
Affiliations
Review

Is the unique camouflage strategy of Pneumocystis associated with its particular niche within host lungs?

Philippe M Hauser. PLoS Pathog. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Fig 1
Fig 1. Structure and organization of the Msg superfamily of Pneumocystis species.
(A) The gene structure of each Msg family in shown with underneath features of the encoded glycoprotein. For Family I, the cross figures recombination between the CRJE sequences involved in mutually exclusive expression of a single gene. In Pneumocystis jirovecii, there are two introns instead of one in Families II and III. Except in Family I, each intron is 20 to 50 bps long. (B) Organization of the msg genes within typical subtelomeres of P. jirovecii. These subtelomeres are from chromosome 6 (top) and 11 (bottom) [9]. CRJE, conserved recombination junction element; GPI, glycosylphosphatidylinositol-anchor signal; LS, leader sequence; Msg, major surface glycoprotein; PE, proline and glutamine-rich region; ST, serine and threonine-rich region; T, threonine-rich region; UCS, upstream conserved element.
See this image and copyright information in PMC

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