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. 2018 Dec 6:12:886.
doi: 10.3332/ecancer.2018.886. eCollection 2018.

ReDO_DB: the repurposing drugs in oncology database

Pan Pantziarka  1   2 , Ciska Verbaanderd  1   3 , Vidula Sukhatme  4 , I Rica Capistrano  1 , Sergio Crispino  1 , Bishal Gyawali  1   5 , Ilse Rooman  1   6 , An Mt Van Nuffel  1 , Lydie Meheus  1 , Vikas P Sukhatme  4   7 , Gauthier Bouche  1
Affiliations

ReDO_DB: the repurposing drugs in oncology database

Pan Pantziarka et al. Ecancermedicalscience. .

Abstract

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

Keywords: ReDO project; cancer drugs; drug repurposing; online database; repositioning.

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Figures

Figure 1.
Figure 1.. World map showing the number of late-stage trials of the drugs in the ReDO_DB per country.
See this image and copyright information in PMC

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