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Review
. 2019 Feb;17(2):1078-1084.
doi: 10.3892/etm.2018.6980. Epub 2018 Nov 16.

The impact of lifestyle factors on evolution of atopic dermatitis: An alternative approach

Iulia Solomon  1 , Mihaela Adriana Ilie  2   3 , Carmen Draghici  1 , Vlad Mihai Voiculescu  1   2 , Constantin Căruntu  4   5 , Daniel Boda  2   5 , Sabina Zurac  6   7
Affiliations
Review

The impact of lifestyle factors on evolution of atopic dermatitis: An alternative approach

Iulia Solomon et al. Exp Ther Med. 2019 Feb.

Abstract

Atopic dermatitis (AD) is a multifactorial chronic inflammatory disease with an incompletely understood etiopathogenesis. With a significant impact on the quality of life of patients, AD has attracted the interest of many research studies aiming to investigate the complex cellular and molecular mechanisms and to identify new therapeutic pathways. Various studies have focused on psycho-immunology, emphasizing the involvement of stress, defined as a general response of the body to external or internal challenges to the AD pathology. Factors like lifestyle and leisure activities may change the behavior of immune cells in AD with a strong impact on the evolution of the disease. Moreover, the poor adherence of AD patient to standard treatment approach has led to the necessity to combine different therapies in the field of complementary and alternative medicine. Although there are still not enough data to conclude that adjuvant therapies are effective in a conventional sense, there are already promising results suggesting that alternative therapeutic strategies could be a main subject of further research.

Keywords: atopic dermatitis; diet; lifestyle; microbioma; neuroendocrine factors; psychoneuroimmunology; stress.

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References

    1. Ellis C, Luger T, Abeck D, Allen R, Graham-Brown RA, De Prost Y, Eichenfield LF, Ferrandiz C, Giannetti A, Hanifin J, et al. ICCAD II Faculty: International Consensus Conference on Atopic Dermatitis II (ICCAD II): Clinical update and current treatment strategies. Br J Dermatol. 2003;148(Suppl 63):3–10. doi: 10.1046/j.1365-2133.148.s63.1.x. - DOI - PubMed
    1. Pickett K, Loveman E, Kalita N, Frampton GK, Jones J. Educational interventions to improve quality of life in people with chronic inflammatory skin diseases: Systematic reviews of clinical effectiveness and cost-effectiveness. Health Technol Assess. 2015;19:1–176. doi: 10.3310/hta19860. - DOI - PMC - PubMed
    1. Lapidus CS, Kerr PE. Social impact of atopic dermatitis. Med Health R I. 2001;84:294–295. - PubMed
    1. Holm JG, Agner T, Clausen ML, Thomsen SF. Quality of life and disease severity in patients with atopic dermatitis. J Eur Acad Dermatol Venereol. 2016;30:1760–1767. doi: 10.1111/jdv.13689. - DOI - PubMed
    1. Apfelbacher C, Heinl D. Health-related quality of life measures in atopic dermatitis: A critical appraisal. Curr Dermatol Rep. 2015;4:155–158. doi: 10.1007/s13671-015-0122-5. - DOI