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. 2019 Jan;98(4):e14275.
doi: 10.1097/MD.0000000000014275.

Efficacy and safety of herbal medicine (Bailemian capsule) for treating insomnia: Protocol for a systematic review and meta-analysis

Tian Tian  1 , Lian Hua  2 , Jianxin Wang  3 , Jingzhi Guan  4
Affiliations

Efficacy and safety of herbal medicine (Bailemian capsule) for treating insomnia: Protocol for a systematic review and meta-analysis

Tian Tian et al. Medicine (Baltimore). 2019 Jan.

Abstract

Background: Insomnia has become a universal subhealth disease, affecting more and more modern people's health and quality of life. At present, western medicine is only symptomatic treatment for insomnia. Bailemian Capsule (BLMC) is a proprietary Chinese medicine for treating insomnia. It has been widely used in China, but lacks evidence for evidence-based medicine. At the same time, the clinical efficacy and safety of BLMC are controversial. Therefore, the effectiveness and safety of BLMC in the treatment of insomnia are studied and systematically evaluated in this study. It provides reliable theoretical support for the treatment of insomnia with Traditional Chinese Medicine and the combination of traditional Chinese and Western medicine.

Methods: The information was retrieved from electronic databases, Cochrane, PubMed, EMBASE, SinoMed, China National Knowledge Infrastructure, VIP Data, and WangFang Data. Randomized controlled trials on the BLMC in the treatment of insomnia were conducted. There was no limitation on the literature language. RevMan 5.3 software and STATA 12.0 software were used to perform the meta-analysis.

Results: This review will be to assess the efficacy and safety of BLMC for insomnia.

Conclusion: Our systematic evaluation will provide evidence for the clinical efficacy and safety of BLMC in the treatment of insomnia, and will be published in the form of academic papers in the future to provide new ideas for clinicians in the treatment of insomnia.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

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Figure 1
Flow chart of study selection.
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References

    1. Zhang LP, Xia M. Analysis and thoughts to current treatment status of insomnia. Glob Tradit Chin Med 2011;4:66–9.
    1. Lind MJ, Hawn SE, Sheerin CM, et al. An examination of the etiologic overlap between the genetic and environmental influences on insomnia and common psychopathology. Depress Anxiety 2017;34:453–62. - PMC - PubMed
    1. Rosekind MR. The epidemiology and occurrence of insomnia. J Clin Psychiatry 1992;53:4–6. - PubMed
    1. Zhang P, Tan CW, Chen GH, et al. Patients with chronic insomnia disorder have increased serum levels of neurofilaments, neuron-specific enolase and S100B: does organic brain damage exist? Sleep Med 2018;48:163–71. - PubMed
    1. Ye ZJ, Liang MZ, Hu Q, et al. Progress of diagnosis and treatment of insomnia disorder. Med Philos 2017;38:60–3.

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