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. 2020 Mar-Apr;86(2):242-246.
doi: 10.1016/j.bjorl.2018.11.009. Epub 2018 Dec 31.

Evaluation of choroidal thickness measurements in patients with marked nasal septal deviation

Selin Üstün Bezgin  1 , Taliye Çakabay  2 , Sadık Etka Bayramoğlu  3 , Nihat Sayın  3 , Murat Koçyiğit  2
Affiliations

Evaluation of choroidal thickness measurements in patients with marked nasal septal deviation

Selin Üstün Bezgin et al. Braz J Otorhinolaryngol. 2020 Mar-Apr.

Abstract
in English, Portuguese

Introduction: Chronic upper airway obstruction due to marked nasal septal deviation may cause chronic hypoxia. It may change the balance of the sympathetic-parasympathetic system and may affect blood flow in the choroid.

Objective: To assess choroidal thickness measurements of patients with marked nasal septal deviation.

Methods: The patients who had nasal obstruction symptoms diagnosed with marked nasal septal deviation by anterior rhinoscopy and nasal endoscopy and scheduled for septoplasty were included in the study. The control group consisted of age, sex and body mass index-matched healthy individuals. The choroidal measurements at the central fovea and 1000μm away from the fovea in the nasal and temporal regions were performed using enhanced depth imaging optical coherence tomography.

Results: In the study group, 52 eyes of 26 patients with a mean age of 26.34±8.14 years were examined. In the control group, 52 eyes of 28 healthy individuals with a mean age of 26.69±7.84 years were examined. There was no statistically significant difference in terms of choroidal thickness measurements between the groups (p>0.05).

Conclusion: Our results suggest that marked nasal septal deviation may not lead to significant hypoxia and sympathetic activation, resulting in deterioration of the choroidal blood flow and consequent choroidal thickening.

Introdução: A obstrução crônica das vias aéreas superiores devido a acentuado desvio do septo nasal pode causar hipóxia crônica. Pode alterar o equilíbrio do sistema simpático-parassimpático e afetar o fluxo sanguíneo na coroide.

Objetivo: Avaliar as medidas da espessura da coroide em pacientes com acentuado desvio de septo nasal.

Método: Foram incluídos no estudo pacientes que apresentavam sintomas de obstrução nasal, com diagnóstico de acentuado desvio de septo realizado por rinoscopia anterior e endoscopia nasal, e com septoplastia programada. O grupo controle consistiu de indivíduos saudáveis pareados por idade, sexo e índice de massa corporal. As medidas da coroide na fóvea central e a 1.000 μm da fóvea nas regiões nasal e temporal foram feitas com tomografia de coerência óptica com imagem de profundidade melhorada.

Resultados: No grupo de pacientes, 52 olhos de 26 pacientes com média de 26,34 ± 8,14 anos foram examinados. No grupo controle, 52 olhos de 28 indivíduos saudáveis com média de 26,69 ± 7,84 anos foram examinados. Não houve diferença estatisticamente significante em termos de medidas da espessura da coroide entre os grupos (p > 0,05).

Conclusão: Nossos resultados sugerem que desvios do septo nasal acentuados podem não levar à hipóxia significativa e ativação simpática, resultar na deterioração do fluxo sanguíneo coroidal e consequente espessamento da coroide.

Keywords: Choroidal thickness; Desvio do septo nasal; Distúrbios respiratórios do sono; Espessura da coroide; Nasal septal deviation; Sleep-disordered breathing.

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References

    1. Ozkececi G., Akci O., Bucak A., Ulu S., Yalim Z., Ayçiçek A., et al. The effect of septoplasty on pulmonary artery pressure and right ventricular function in nasal septum deviation. Eur Arch Otorhinolaryngol. 2016;273:3747–3752. - PubMed
    1. Fidan V., Aksakal E. Impact of septoplasty on pulmonary artery pressure in patients with markedly deviated septum. J Craniofac Surg. 2011;22:1591–1593. - PubMed
    1. Unlu I., Kesici G.G., Oneç B., Yaman H., Guçlu E. The effect of nasal obstruction on mean platelet volume in patients with marked nasal septal deviation. Eur Arch Otorhinolarnygol. 2016;273:401–405. - PubMed
    1. Uluyol S., Kılıçaslan S., Gur M.H., Karakaya N.E., Buber I., Ural S.G. Effects of nasal septum deviation and septoplasty on Cardiac Arrhythmia risk. J Otolaryngol Head Neck Surg. 2016;155:347–352. - PubMed
    1. Nickla D., Wallman J. The multifunctional choroid. Prog Retin Eye Res. 2010;29:144–168. - PMC - PubMed