Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Dec:30:6-10.
doi: 10.1016/j.copsyc.2018.12.009. Epub 2018 Dec 19.

Non-invasive brain stimulation in substance use disorders: implications for dissemination to clinical settings

Affiliations
Review

Non-invasive brain stimulation in substance use disorders: implications for dissemination to clinical settings

Elena R Stein et al. Curr Opin Psychol. 2019 Dec.

Abstract

With expanding knowledge of how neural circuitry is disrupted in substance use disorders (SUD), non-invasive brain stimulation (NIBS) techniques have emerged as potential strategies to directly modulate those neural circuits. There is some evidence supporting the two most common forms of NIBS, transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), in the treatment of SUD. Yet results of recent studies have been mixed and critical methodological issues must be addressed before strong conclusions can be drawn. This review highlights recent evidence of NIBS for SUD, addressing the impact of stimulation on relevant clinical and cognitive outcomes in substance-using populations. Additionally, we aim to bring a clinical perspective to the opportunities and challenges of implementing neuromodulation in SUD treatment.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

The authors declare no conflicts of interest related to the contents of this paper.

References

    1. Koob GF, Volkow ND: Neurocircuitry of addiction. Neuropsychopharmacology 2010, 35:217–238. - PMC - PubMed
    1. Feil J, Zangen A: Brain stimulation in the study and treatment of addiction. Neurosci Biobehav Rev 2010, 34:559–574. - PubMed
    1. Polanía R, Nitsche MA, Ruff CC: Studying and modifying brain function with non-invasive brain stimulation. Nat Neurosci 2018, 21:174–187. - PubMed
    1. Radman T, Ramos RL, Brumberg JC, Bikson M: Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimul 2009, 2:215–228.e3. - PMC - PubMed
    1. Nitsche MA, Fricke K, Henschke U, Schlitterlau A, Liebetanz D, Lang N, Henning S, Tergau F, Paulus W: Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol 2003, 553:293–301. - PMC - PubMed

Publication types

MeSH terms