Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
- PMID: 30687065
- PMCID: PMC6341312
- DOI: 10.1159/000495032
Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
Abstract
Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid tumors. Thrombocytopenia with traditional chemotherapy agents is most frequently the result of megakaryocyte cytotoxicity. Oxaliplatin is a platinum derivative commonly used in gastrointestinal malignancies and is associated with drug-induced immune thrombocytopenia.
Keywords: Adenocarcinoma; Oxaliplatin; Thrombocytopenia.
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